Protein Alignment Cyp6a9 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001028858.2
• Gene: Cyp4f18 / 290623
• RGDID: 1305261
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 495
• Identity: 122/495 - (24%)
• Similarity: 225/495 - (45%)
• Gaps: 77/495 - (15%)

  Fly    37 EEPHILMGSLTGVQTSRSFSAIWMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNK 101
            ||..:.:.||:  :|.|.....|:         ||     |  .|.|.:...:..|.:::...:.
  Rat    71 EEGLLYIQSLS--RTFRDVCCWWV---------GP-----W--HPVIRIFHPAFIKPVILAPASV 117

  Fly   102 F-TDRGFYHNTEDDPLSGQ-LFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQ 164
            . .||.||...:  |..|. |.|..|.||...|..|:..|....:|           .::::|..
  Rat   118 APKDRVFYRFLK--PWLGDGLLLSTGDKWSRHRHMLTPAFHFNILK-----------PYVKIFND 169

  Fly   165 ------------AMEKSPIVEVRDILARFTTDVIGTCAFGIECSSLKDPEAEF--RVMGRRAIFE 215
                        |.:.|..:::.:.::..|.|.:..|.|..: |:.::..:|:  .::...|:..
  Rat   170 STNIMHAKWQRLASQGSARLDMFEHISLMTLDSLQKCVFSFD-SNCQEKPSEYITAILELSALVA 233

  Fly   216 QRHGPIGIAFINSFQNLAR-RLHMKITLEEAEHFFLRIVRE---TV-------AFREKNNIRRND 269
            :||..: :.:::.|.:|.| .:..:........|...::||   |:       |.:.|...:..|
  Rat   234 RRHQSL-LLYVDLFYHLTRDGMRFRKACRLVHDFTDAVIRERRRTLPDQGGDDALKAKAKAKTLD 297

  Fly   270 FMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRV 334
            |:|.|:      |:|.|.||:  |:.|::.|:|..|...|.:|:::.:.:.||.||:|.:.|:|.
  Rat   298 FIDVLL------LSKDEHGEA--LSDEDIRAEADTFMFGGHDTTASGLSWILYNLAKHPEYQERC 354

  Fly   335 RKECQEVI-GKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVP-GHPKYVIKK 397
            |:|.:|:: .:...||.::.:..:.:|...|.|:|||:.....::|.|.:|..:| |.   ||.|
  Rat   355 RQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPATAISRCCTQDIMLPDGR---VIPK 416

  Fly   398 GMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSG 462
            |:...|.....|.:..::.:|..:||..|..:..:.|..:.::||..|||||||..|...:.:..
  Rat   417 GVICRISIFGTHHNPAVWPDPEVYNPFRFDADNGEGRSPLAFIPFSAGPRNCIGQTFAMSEMKVA 481

  Fly   463 LALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKVE 502
            |||.:.||:  |......|  ..|...::.:|.|::|:||
  Rat   482 LALTLLRFR--VLPDDKEP--RRKPELILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	112/458 (24%)
Cyp4f18	NP_001028858.2	CYP4F	74..515	CDD:410772	117/488 (24%)