Protein Alignment Cyp6a9 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 134/547 - (24%)
• Similarity: 234/547 - (42%)
• Gaps: 103/547 - (18%)

  Fly     5 SVLLAIVVVLVGYLLLKWRRALHYWQNLDIP-CEEPHILMGSLTGVQTSRS--FSAIWMDYYNKF 66
            :|||.|:.:||.| ..||:      |...|| ....:.|:|....::.:.:  |..| :.|..:|
  Rat    28 TVLLNILQMLVSY-ARKWQ------QMRPIPSVARAYPLVGHALFMKPNNTEFFQQI-IQYTEEF 84

  Fly    67 R---------GTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQLFL 122
            |         |..|....|..:...:::..            :|..|:.|.:......|...|..
  Rat    85 RHLPIIKLWIGPVPLVALYKAENVEVILTS------------SKQIDKSFMYKFLQPWLGLGLLT 137

  Fly   123 LDGQKWKSMRSKL--SYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFT--- 182
            ..|.||::.|..|  |:.||      :....:.|.:|...:....:||....|..:.....|
  Rat   138 STGSKWRARRKMLTPSFHFT------ILEDFLDVMNEQANILVNKLEKHVNQEAFNCFFPITLCA 196

  Fly   183 TDVIGTCAFGIECSSLKDPEAEF-RVMGRRA-------------------IF-EQRHGPIGIAFI 226
            .|:|...|.|....:..:.::|: |.:.|.:                   :| |.|....|:..:
  Rat   197 LDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFWFDLWYLMFKEGRDHKKGLKSL 261

  Fly   227 NSFQN--LARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESGE 289
            ::|.|  :|.|::.:    :||...:...|..:..:.|    |..|:|.|:.:.:.        |
  Rat   262 HTFTNNVIAERVNAR----KAEQDCIGAGRGPLPSKTK----RKAFLDLLLSVTDE--------E 310

  Fly   290 SVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESM 354
            ...|:.|::..:...|...|.:|::..:.::||.|..:.::|.:|.||..:|.|:.:..:|.|.:
  Rat   311 GNKLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRSHRPVTLEDL 375

  Fly   355 KDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPN 419
            |.:.|||.||.||||::..:|:..|...||.||.|   |.|.||...:|...|:|||.:.:.:|.
  Rat   376 KKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAG---YKISKGTEAVIIPYALHRDPRYFPDPE 437

  Fly   420 TFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVY 484
            .|.|:.|.||..:.|....::||..|||||||.:|..|:.::.||.::..|.          |..
  Rat   438 EFQPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREFW----------IES 492

  Fly   485 SKK--------TFLISSETGIFLKVER 503
            ::|        ..::....||::|::|
  Rat   493 NQKREELGLAGDLILRPNNGIWIKLKR 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	112/465 (24%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	117/486 (24%)