Protein Alignment Cyp6a9 and Cyp17a1

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_036885.2
• Gene: Cyp17a1 / 25146
• RGDID: 2456
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 122/543 - (22%)
• Similarity: 199/543 - (36%)
• Gaps: 126/543 - (23%)

  Fly    14 LVGYLLLKWRRALHYW-----QNLDIPCEEPHI-LMGSLTGVQTSRSFSAIWMDYYNKFRGTGPF 72
            |||.|||  ..|..:|     ....:|...|.: |:|||..:.........:.....|:   ||.
  Rat     4 LVGLLLL--ILAYFFWVKSKTPGAKLPRSLPSLPLVGSLPFLPRRGHMHVNFFKLQEKY---GPI 63

  Fly    73 AGFYWFQRPGILVLDISLAKLILIKEFNKFTDRG--FYHNTEDDPLSGQLFLLDGQKWKSMRSKL 135
            ..........:::....||:.:|||:..:|:.|.  ...:...|...|..|...|..|...|..:
  Rat    64 YSLRLGTTTTVIIGHYQLAREVLIKKGKEFSGRPQMVTQSLLSDQGKGVAFADAGSSWHLHRKLV 128

  Fly   136 SYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDI-----------------LARFTT 183
            ..||:..|                  .||.:||....|.:.:                 :....|
  Rat   129 FSTFSLFK------------------DGQKLEKLICQEAKSLCDMMLAHDKESIDLSTPIFMSVT 175

  Fly   184 DVIGTCAFGIECSSLKDP---------EAEFRVMGRR---------AIFEQRHGPIGIAFINSFQ 230
            ::|....|.|.... |||         |......|.|         .||..:    |:..|..:
  Rat   176 NIICAICFNISYEK-KDPKLTAIKTFTEGIVDATGDRNLVDIFPWLTIFPNK----GLEVIKGY- 234

  Fly   231 NLARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRR-NDFMDQLIDLK-NSPLTKSESGESVNL 293
                   .|:..|.....|.:.       |||.:.:. :...|.||..| ||....|..|...::
  Rat   235 -------AKVRNEVLTGIFEKC-------REKFDSQSISSLTDILIQAKMNSDNNNSCEGRDPDV 285

  Fly   294 -TIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDM 357
             :...:.|.....||||.||::|.:.:.|..|..:.:::.:::||..:.:| ::...|:.....:
  Rat   286 FSDRHILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVG-FSRTPTFNDRSHL 349

  Fly   358 VYLDQVISETLRLYTVLPVLNRECLEDYEVPGHP--------KYVIKKGMPVLIPCGAMHRDEKL 414
            :.|:..|.|.||:..|.|:|         :| |.        ::.:.|...|::...|:|.||..
  Rat   350 LMLEATIREVLRIRPVAPML---------IP-HKANVDSSIGEFTVPKDTHVVVNLWALHHDENE 404

  Fly   415 YANPNTFNPDNF---------SPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRF 470
            :..|:.|.|:.|         :|.:       .:||||.|||:|||....:.:.....|||:.||
  Rat   405 WDQPDQFMPERFLDPTGSHLITPTQ-------SYLPFGAGPRSCIGEALARQELFVFTALLLQRF 462

  Fly   471 KFSVCEQTTIPIVYS--KKTFLI 491
            ...|.:...:|.:..  |..|||
  Rat   463 DLDVSDDKQLPRLEGDPKVVFLI 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	107/483 (22%)
Cyp17a1	NP_036885.2	CYP17A1	60..490	CDD:410766	107/485 (22%)