Protein Alignment Cyp6a9 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_663708.1
• Gene: Cyp4x1 / 246767
• RGDID: 628719
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 135/539 - (25%)
• Similarity: 235/539 - (43%)
• Gaps: 98/539 - (18%)

  Fly     8 LAIVVVLVGYLLLKWRRALHYWQNLDI---PCEEPHILMGSLTGVQ--TSRSFSAIWMDYYNKFR 67
            ||:|::....|.|:.:|.|.     |:   |....|.|:|....:|  .......|..:|...|.
  Rat    22 LALVLMQAVKLYLRRQRLLR-----DLRPFPGPTAHWLLGHQKFLQEDNMEKLDEIVKEYPCAFP 81

  Fly    68 -GTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTD--RGFYHNTEDDPLSGQLFLLDGQKWK 129
             ..|||..|::       :.|...||:.|.:     ||  ..:.|......|...|..|||.:|.
  Rat    82 CWVGPFQAFFY-------IYDPDYAKIFLSR-----TDPKTQYLHQLMTPFLGRGLLNLDGPRWF 134

  Fly   130 SMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKS-----PIVEVRDILARFTTDVIGTC 189
            ..|..|:..|....:|   |.|..:.|. :.:.....||:     ..:||.:.:...|.|:|..|
  Rat   135 QHRCLLTPAFHQDILK---PCVDMMAHS-VNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKC 195

  Fly   190 AFGIECSSLKDPEAEFRVMGRRAIFE-------------QRH------GPIGIAFINSFQNLARR 235
            |||.|.:...:...|..|   :|.||             ..|      .|.|    :.||.|.:.
  Rat   196 AFGQETNCQINGTYESYV---KATFELGEIISSRLYNFWHHHDIIFKLSPKG----HCFQELGKV 253

  Fly   236 LHM---KITLEEAEHFFLRIVRETVAFREKNNIRRND------FMDQLIDLKNSPLTKSESGESV 291
            :|.   ||..:.         ::|:    |:.:.::|      |:|.::        .:::|:..
  Rat   254 IHQCTEKIIQDR---------KKTL----KDQVNQDDTQTSQNFLDIVL--------SAQAGDEK 297

  Fly   292 NLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKD 356
            ..:..::.::...|..||.:.|:.::.:.||.||.:.:.|||.|.|.:.::|. ...||:|.:.:
  Rat   298 AFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGD-GSSITWEQLDE 361

  Fly   357 MVYLDQVISETLRLYTVLPVLNRECLEDYEVP-GHPKYVIKKGMPVLIPCGAMHRDEKLYANPNT 420
            :.|....|.|||||...:|.::||..:...:| ||.   :..||.|::....:|.:..::.:|..
  Rat   362 IPYTTMCIKETLRLIPPIPSISRELSKPLTLPDGHS---LPAGMTVVLSIWGLHHNPAVWKDPKV 423

  Fly   421 FNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYS 485
            |:|..|:.|..::|....:|||..|||||||.:|..::.:..:||.:.||:  |....|.|..:|
  Rat   424 FDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFR--VAADLTRPPAFS 486

  Fly   486 KKTFLISSETGIFLKVERV 504
            ..| ::..:.||:|.::::
  Rat   487 SHT-VLRPKHGIYLHLKKL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	117/465 (25%)
Cyp4x1	NP_663708.1	CYP4B-like	66..500	CDD:410771	121/484 (25%)