Protein Alignment Cyp6a9 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 135/554 - (24%)
• Similarity: 228/554 - (41%)
• Gaps: 121/554 - (21%)

  Fly     1 MGVY-SVLLAIVVVLVGYLLL----KWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAI-- 58
            :|:: ||::.:|:||..:.||    |..||:.     ..|....|.|.|....:|...|...:
  Rat    13 LGLWASVVILMVIVLKLFSLLLRRQKLARAMD-----SFPGPPTHWLFGHALEIQKLGSLDKVVS 72

  Fly    59 WMDYYNKFRGTGPFAGFYWF-QRPGIL-VLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQ-- 119
            |...:       |.|...|| |..|.| :.:...||.:.        .||       ||.:..
  Rat    73 WAQQF-------PHAHPLWFGQFVGFLNIYEPDYAKAVY--------SRG-------DPKAADVY 115

  Fly   120 ----------LFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAM-------- 166
                      |.:|||.||...|..|:..|....:|           .::.:|.::.
  Rat   116 DFFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDVLK-----------PYVAIFAESTRMMLDKWE 169

  Fly   167 EKSPIVEVRDI---LARFTTDVIGTCAFGIECSSL--KDPEAEFRVMGRRAIFEQRHGPIGIAFI 226
            :|:...:..||   :.....|.:..|.||...|.|  :|......|.....:.:||        |
  Rat   170 KKASENKSFDIFCDVGHMALDTLMKCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQR--------I 226

  Fly   227 NSFQNLARRLHMKITLEEAEH--FFLR-----------IVRETVAF------REKNNIRRN-DFM 271
            :|||     .|.........|  .|||           ::|:..|.      |:|...||: ||:
  Rat   227 DSFQ-----YHNDFIYWLTPHGRRFLRACKIAHDHTDEVIRQRKAALQDEKERKKIQQRRHLDFL 286

  Fly   272 DQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRK 336
            |.|:.:::      |||  :.|:..|:.|:...|...|.:|:::.:.:.||.:|.:.:.|...|:
  Rat   287 DILLGVRD------ESG--IKLSDAELRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCRE 343

  Fly   337 ECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYE-VPGHPKYVIKKGMP 400
            |.:.::|..: ...::.:..|.||...:.|..|||..:|.:.|:..:... |.|..   :..|..
  Rat   344 EVRGILGDQD-SFQWDDLAKMTYLTMCMKECFRLYPPVPQVYRQLNKPVTFVDGRS---LPAGSL 404

  Fly   401 VLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLAL 465
            :.:...|:||:..::.:|..|:|..||||....|....::||..|||||||.:|...:.:...||
  Rat   405 ISLHIYALHRNSTVWPDPEVFDPLRFSPENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTAL 469

  Fly   466 LINRFKFSVCEQTTIPIVYSKKTFLISSETGIFL 499
            .:.||:||: :.:.:||...:  .::.|:.||.|
  Rat   470 CLLRFEFSL-DPSKMPIKVPQ--LILRSKNGIHL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	115/477 (24%)
Cyp4b1	NP_058695.2	CYP4B-like	67..501	CDD:410771	118/495 (24%)