Protein Alignment Cyp6a9 and Cyp4a29

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001093653.1
• Gene: Cyp4a29 / 230639
• MGIID: 3717143
• Length: 509
• Species: Mus musculus
• Alignment Length: 548
• Identity: 127/548 - (23%)
• Similarity: 214/548 - (39%)
• Gaps: 114/548 - (20%)

  Fly    11 VVVLVGYLLLKWRRALHYWQN-------LDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNKFRG 68
            |:.|:|.|||.::.|.||.:.       ...|....|.|.|.....:.......| :.|..||
Mouse    21 VIFLIGLLLLLFKAAQHYLRRQWLLRALYQFPSPPSHWLFGHCLQFKVDEELRWI-LRYLEKF-- 82

  Fly    69 TGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQ-LFLLDGQKWKSMR 132
            .|.|..:.|.....|.|.|....|:||.:...|.:...|.     .|..|. ||.|:|.:|...|
Mouse    83 PGAFLHWIWGSHVFIKVCDPDYMKVILGRADPKASLYRFL-----TPWLGHGLFFLNGDEWFQHR 142

  Fly   133 SKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFGIECSS 197
            ..|:..|....:|    ..|.:..:.::|.   :||...:..:||...
Mouse   143 RLLTPAFHYDILK----PYVGIMADSVQVM---LEKWEQIACQDITLE----------------- 183

  Fly   198 LKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKITLEEAEHFFLRIVRE---TVAF 259
                           ||.    ||.:..:::....|......:.|:.:...:|:.|.:   .|..
Mouse   184 ---------------IFH----PISLMMLDTIMKYAFSYQGSVQLDRSSQAYLQAVSDLNNLVTS 229

  Fly   260 REKNNIRRNDFM---------------------DQLIDLKNSPLTKSESGESV------------ 291
            |.||....||.:                     |:::.|:.:.|..::|.:.:
Mouse   230 RMKNVFLHNDIIYNLTSHSRRTNSACQIAHEHTDRVVKLRKAQLQDNKSMKKLRGKRCLDFLDIL 294

  Fly   292 -------NLTIEEMAAQAFV---FFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYN 346
                   ..::.:.|.:|.|   .|| |.:|.::.:.:..|.||.|.|.|.|.|:|.|.::|. .
Mouse   295 LLSRMDDGSSLSDKALRAEVDSLMFG-GHDTPASGISWVFYALATHPDHQQRCREEVQSLLGD-G 357

  Fly   347 GEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRD 411
            ..||::.:..|.|....|.|.||||..:|.:.|:.......|....  :.||:.||:...|:|.:
Mouse   358 SPITWDHLHQMPYTTMCIKEALRLYPPIPSVGRKLSTPVTFPDGRS--LPKGITVLLHFYALHHN 420

  Fly   412 EKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCE 476
            .|::.||..|:|..|:...|:.  |..:|||..|.|||||........:..:||.:.||:. :.:
Mouse   421 PKVWPNPEVFDPSRFAMNSVQH--SHAFLPFSGGSRNCIGKHLAMNVLKVAVALTLLRFEL-LPD 482

  Fly   477 QTTIPIVYSKKTFLISSETGIFLKVERV 504
            .:.:||  ..:..::.|:.||:|.:.::
Mouse   483 PSRVPI--PTQQLVLKSKNGIYLHLRKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	108/476 (23%)
Cyp4a29	NP_001093653.1	CYP4B-like	75..504	CDD:410771	113/488 (23%)