Protein Alignment Cyp6a9 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 135/544 - (24%)
• Similarity: 223/544 - (40%)
• Gaps: 100/544 - (18%)

  Fly     3 VYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAI----WMDYY 63
            |.:|..:|.:.::.|.|..|.    ||....:........:|.|..:....:...|    |...|
 Worm     6 VLAVTFSIFLGILTYYLWIWT----YWMRKGVKGPRGRPFVGVLDVLLEHETPGLIKLGEWTKKY 66

  Fly    64 NKFRG--TGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSG-------- 118
            .|..|  .|.       ||. ::|.|.::...|.:|:|:.|..|..      :|:.|
 Worm    67 GKVYGYTDGT-------QRT-LVVADPAMVHEIFVKQFDNFYGRKL------NPIQGNPEKEQRV 117

  Fly   119 QLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTT 183
            .|....|.:||.:|:..|.:|::..:|.|..||.....|.:....:.......:::......:|.
 Worm   118 HLLAAQGYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQEYTM 182

  Fly   184 DVIGTCAFG-----------------IECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQN 231
            ||||..|.|                 |.|.|.|:          ..:..|...||| .||
 Worm   183 DVIGRFAMGQTDSMMFKNPIVNVVREIFCGSRKN----------LMLICQVFPPIG-QFI----- 231

  Fly   232 LARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRR--------NDFMDQLIDLKNSPLT-KSES 287
              |.|..|.....|...: .|:::.||.|.....|.        .||:|..:|.::..:. .:|:
 Worm   232 --RDLTFKFPRIPAFKLY-SIMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEA 293

  Fly   288 GESVN---------LTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIG 343
            .|..:         |:.:|:..|.|:|...||:|::.::.:..|.||.:..||::|.:|.....|
 Worm   294 REDFSKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFG 358

  Fly   344 KYNGEITYESMKDMVYLDQVISETLRLYTVLPVLN-RECLEDYEVPGHPKYVIKKGMPVLIPCGA 407
              ..|:.:|.:..:.|:|.||.|.||||.:..:.| |:|::...|.|   ..|:.|:.|.:...:
 Worm   359 --TSEVEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNG---VKIEAGVYVQMDTWS 418

  Fly   408 MHRDEKLYA-NPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFK 471
            :|.|.:|:. :...|.|:.:|.:...|.... :||||.|||.|||||...|:.:..|..|:..:.
 Worm   419 LHYDPELWGEDVKEFKPERWSTDEPLEHKGA-YLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYT 482

  Fly   472 FSVCEQTTIPIVYSKKTFLISSET 495
            |....:|.||:.      |:.|.|
 Worm   483 FETGNKTRIPLK------LVGSAT 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	121/475 (25%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	123/481 (26%)