Protein Alignment Cyp6a9 and cyp-13A6

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_496113.1
• Gene: cyp-13A6 / 188357
• WormBaseID: WBGene00011673
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 138/545 - (25%)
• Similarity: 240/545 - (44%)
• Gaps: 122/545 - (22%)

  Fly    41 ILMGSLT------------GVQTSRSFSAIWM-----DYYN----KFRG----TGPFAGFYWFQR 80
            :|:|..|            |::..|.|..|.|     |:.|    |:|.    .||..||....:
 Worm     9 VLLGVFTYSVWIWSYFIRKGIKGPRGFPGIGMLIQTIDHENPPFLKYRDWTKQYGPVYGFTEGPQ 73

  Fly    81 PGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSG--------QLFLLDGQKWKSMRSKLSY 137
            ..:::.:..:...|..|:|:.|..|..      .|:.|        .:|...|::||.:|:..|.
 Worm    74 QTMIISEPEMVNEIFKKQFDNFYGRKL------RPIIGDPEKDKRVNIFSTQGKRWKRLRTLSSP 132

  Fly   138 TFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFG-IECSSLKDP 201
            :|::..::.:..:|.:.|.|.:....|.:.|:..:::..:...:|..||...|.| .|.:..|:|
 Worm   133 SFSNNSLRKVRNSVQECGTEILWNIEQKVRKNEDIDMLIVYQEYTLGVISRIALGQSESNMFKNP 197

  Fly   202 -----EAEFR-------VMG----RRAIFEQRHGPIGIAFINSFQNLARRLHMKI--TLEEAEHF 248
                 :|.|.       :.|    ...:|.:....:..:||.:|         ||  .:|.|
 Worm   198 LLPKVQAIFNGSWHVFLITGIFPPLAGVFRKMSKMLPASFIPAF---------KIFDLIEVA--- 250

  Fly   249 FLRIVRETVAFREKNNIR------RNDFMDQLIDLKNSPLTKSESGES-----------VN--LT 294
                |:..:..|.|:.|:      ..||:|..:|.: .|..|..|||:           :|  ||
 Worm   251 ----VQARIDQRAKDEIKGVEPGEPQDFIDLFLDAR-VPDVKILSGEANEDFAKSSVVKINKELT 310

  Fly   295 IEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDI----QDRVRKECQEVIGKYNGEITYESMK 355
            .:|:.||.|||..|||:|::.::.:|.|.||.|.:|    |:.|.:||.:      .||.::.:.
 Worm   311 FDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEVDRECPD------PEIFFDHLS 369

  Fly   356 DMVYLDQVISETLRLYTVLPVLN-RECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPN 419
            .:.||:.|:.||||||.:....| |:|:.:..:.|   ....:||.:.:....:|.:.:::..
 Worm   370 KLKYLECVMKETLRLYPLGTTANTRKCMRETTING---VNFDEGMNIQVDTWTLHHNPRIWGE-- 429

  Fly   420 TFNPDNFSPERVKERDSVE-------WLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQ 477
              :.::|.||| .|..:.|       ::|||.|||.|||||..||:.:..||.::..:.|...:.
 Worm   430 --DVEDFKPER-WENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFRTTKN 491

  Fly   478 TTIPIVYSKKTFLISSETGIFLKVE 502
            |.||:....|  |..|...:.:|:|
 Worm   492 TQIPVKLVGK--LTLSPESVIVKLE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	124/491 (25%)
cyp-13A6	NP_496113.1	CYP3A-like	61..511	CDD:410678	124/488 (25%)