Protein Alignment Cyp6a9 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 141/563 - (25%)
• Similarity: 237/563 - (42%)
• Gaps: 118/563 - (20%)

  Fly     5 SVLL--AIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAI-----WMDY 62
            |:|:  |..:.|:.|.:..|    .:|..               .||:..|.|...     :.||
 Worm     4 SILIAGASFIGLLTYYIWIW----SFWIR---------------KGVKGPRGFPFFGVIHEFQDY 49

  Fly    63 YNK--------FRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSG- 118
            .|.        .:..||..|........::|.:......:.:|:|:.|..|      :.:|:.|
 Worm    50 ENPGLLKLGEWTKEYGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGR------KTNPIQGD 108

  Fly   119 -------QLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRD 176
                   .|....|.:||.:|:..|.||::..::.:..||.:...|.:.....|..|...|::.|
 Worm   109 PNKNKRAHLVSAQGHRWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAKGKAVDLLD 173

  Fly   177 ILARFTTDVIGTCAFG-IECSSLKDP-------------EAEFRVMGRRAIFEQRHGPIGIAFIN 227
            ....||.|:||..|.| .|....::|             :..|.|.|   ||... |.:...|..
 Worm   174 YYQEFTLDIIGRIAMGQTESLMFRNPMLPKVKGIFKDGRKLPFLVSG---IFPIA-GTMFREFFM 234

  Fly   228 SFQNLARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRRN----DFMDQLIDLK-NSPLTKSES 287
            .|.::.....:..|:|:|    |....|..|..||..|..:    ||:|..:|.: |....:.||
 Worm   235 RFPSIQPAFDIMSTVEKA----LNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEES 295

  Fly   288 G----------ESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDI----QDRVRKEC 338
            .          ....||.:|:..|.|||..||::|::.::.::.|.||:|.:|    |:.|.:||
 Worm   296 ALGFAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDREC 360

  Fly   339 QEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVL-NRECLEDYEVPGHPKYVIKKGMPVL 402
            .      |.|:|::.:..:.|::.|:.|.||:|.:..:: ||:|:::..|.|   ..|:||..|.
 Worm   361 P------NPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVLG---VQIEKGTNVQ 416

  Fly   403 IPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSV-----EWLPFGDGPRNCIGMRFGQMQARSG 462
            :....:|.|.|::..    :.:.|.|||.:..|.:     .:||||.|||.|||||...|:.:..
 Worm   417 VDTWTLHYDPKVWGE----DANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKML 477

  Fly   463 LALLINRFKFSVCEQTTIPIVYSKKTFLISSET----GIFLKV 501
            |..::.::.|....||.||:.      |:.|.|    .:.||:
 Worm   478 LTHILKKYTFETSTQTEIPLK------LVGSATTAPRSVMLKL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	125/480 (26%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	125/480 (26%)