Protein Alignment Cyp6a9 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 137/546 - (25%)
• Similarity: 235/546 - (43%)
• Gaps: 103/546 - (18%)

  Fly     6 VLLAIVVVLVGYL---LLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAI----WMDYY 63
            :.|||:..::|.|   |..|    .||:...|.....:.::||...:.:|.:...:    |...|
 Worm     4 IFLAILTSIIGVLSFYLWTW----SYWKRRGIAGPSGYPILGSALEMLSSENPPYLQLKEWTKQY 64

  Fly    64 NKFRGTGPFAGFYWFQRPG----ILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSG------ 118
            .|..|.          ..|    :::.|..|.:.:.:|:::.|..|..      :|:.|
 Worm    65 GKVYGI----------TEGLSRTLVISDPDLVQEVFVKQYDNFFGRKL------NPIQGDPNKDK 113

  Fly   119 --QLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARF 181
              .||...|.:||.:|:..|.||::..::.:..||.:...|.:....|..:....:::.|....|
 Worm   114 RVNLFSSQGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQHTDGGQPIDLLDFYQEF 178

  Fly   182 TTDVIGTCAFG-IECSSLKDPEAEFRVMGRRAIF-EQRH------------GPIGIAFINSFQNL 232
            |.||||..|.| .:....|:|...:    .||:| |.|.            |||....:.|..|:
 Worm   179 TLDVIGRIAMGQTDSQMFKNPLLPY----VRAVFGEPRKGLFLSGSLAPWIGPILRMVMFSLPNI 239

  Fly   233 ARRLHMKITLEEAEHFFLRIVRETVAFR---EKNNI---RRNDFMDQLIDLK--------NSPLT 283
            .:...:.:....:     ..|.:.|..|   ||..|   ...||:|..:|.|        |...|
 Worm   240 VKNPAVHVIRHTS-----NAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDFT 299

  Fly   284 KSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQH----QDIQDRVRKECQEVIGK 344
            |:....:..||.||:..|.|||..|||:|::.::.::.:.||.|    :.:|:.:.:||.:
 Worm   300 KAGVKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDRECAD---- 360

  Fly   345 YNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMH 409
              .|:|::.:..:.|::.||.||||:|.:..:.|..|.......|:  |.|.:|..:|.....:|
 Worm   361 --PEVTFDQLSKLKYMECVIKETLRMYPLGALANSRCCMRATKIGN--YEIDEGTNILCDTWTLH 421

  Fly   410 RDEKLYANPNTFNPDNFSPERVKERD-----SVEWLPFGDGPRNCIGMRFGQMQARSGLALLINR 469
            .|:.::..    :.:.|.|||.:..|     ...::|||.|||.|||||...|:.:..|:.::.:
 Worm   422 SDKSIWGE----DAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRK 482

  Fly   470 FKFSVCEQTTIPIVYSKKTFLISSET 495
            :...||.:|.||:.      ||.|.|
 Worm   483 YTLEVCNKTQIPLK------LIGSRT 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	121/477 (25%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	123/483 (25%)