Protein Alignment Cyp6a9 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 486
• Identity: 138/486 - (28%)
• Similarity: 236/486 - (48%)
• Gaps: 33/486 - (6%)

  Fly     5 SVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNKF--- 66
            |::::|....: |::|..|......:.:.:...|||..:|:|.  ||:.....:..|..|::
 Worm     8 SLVISIFTFFI-YIILARRERFKLREKIGLSGPEPHWFLGNLK--QTAERKEKLGYDDANRWFNE 69

  Fly    67 --RGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQLFLLD-GQKW 128
              ...|...|.|:..:..|::.:....|.:.||.|:.|:||......|.:.|:..|.:.. ...|
 Worm    70 LHEQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNSYSSGW 134

  Fly   129 KSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFGI 193
            |..||.::..|::||||.|..|:......|:::..:........::.|.....|.||||.|||.|
 Worm   135 KHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIGKCAFAI 199

  Fly   194 ECSSLKDPEAEFRVMGRRAI--FEQRHGPIGIA--FINSFQNLARRLHMKITLEEAEHFFLRIVR 254
            :.:..:|....|.|..::.|  .:.||..|..|  .:.......:.|:....|.:||   :.:|.
 Worm   200 DSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVLLPELSTFWKALYKYTPLADAE---IPLVE 261

  Fly   255 ETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGF 319
            ......|:   ||.......:||....|.: |..:|..:|.:|:....|.|..||:||:||.|.:
 Worm   262 GLSNVYER---RRGGEGSDSVDLLKLLLNR-EDDKSKPMTKQEVIENCFAFLLAGYETTSTAMTY 322

  Fly   320 ALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLY-TVLPVLNRECLE 383
            ..|.|:::.::|.::.:|..|  .|.||.:||:|:.:|.|||.|..||||.| .|:..:.|.|.|
 Worm   323 CSYLLSKYPNVQQKLYEEIME--AKENGGLTYDSIHNMKYLDCVYKETLRFYPPVIHFIRRLCRE 385

  Fly   384 DYEVPG--HPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKER-DSVEWLPFGDG 445
            |..:.|  :||..|...:|     ..:||:.:.:.:|..|:|:.|  |..:|: .|::|:|||.|
 Worm   386 DITIRGQFYPKGAIVVCLP-----HTVHRNPENWDSPEEFHPERF--ENWEEKSSSLKWIPFGVG 443

  Fly   446 PRNCIGMRFGQMQARSGLALLINRFKFSVCE 476
            ||.|:||||.:|:.::.:..|::.|:....|
 Worm   444 PRYCVGMRFAEMEFKTTIVKLLDTFELKQFE 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	124/418 (30%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	124/418 (30%)