Protein Alignment Cyp6a9 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 555
• Identity: 126/555 - (22%)
• Similarity: 227/555 - (40%)
• Gaps: 123/555 - (22%)

  Fly     1 MGVYSVLLAIVVVLVGYLLLKWRRALHYWQNL-----DIPCEEPHILMGSLTGVQTSRSFSAI-- 58
            :|:::.::.::|.::..|.|.:||     |.|     ..|....|.|.|....:|.:.....:
Mouse    13 LGLWASVVILMVTVLKLLSLLFRR-----QKLARALDSFPGPPKHWLFGHALEIQKTGGLDKVVT 72

  Fly    59 WMDYYNKFRGTGPFAGFYWFQRPGILVLDI---SLAKLILIKEFNKFTDRGFYHNTEDDP----- 115
            |.:.:       |:|...|..: .|:.|:|   ..||.:.        .||       ||
Mouse    73 WTEQF-------PYAHPLWLGQ-FIVFLNIYEPDYAKAVY--------SRG-------DPKAAYV 114

  Fly   116 -------LSGQLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAM------- 166
                   :...|.:|:|.||...|..|:..|....:|           .::.:|.::.
Mouse   115 YDFFLQWIGKGLLVLEGPKWFQHRKLLTPGFHYDVLK-----------PYVAIFAESTRVMLDKW 168

  Fly   167 -EKSPIVEVRDI---LARFTTDVIGTCAFGIECSSLKDPEAEF--------RVMGRRAIFEQRHG 219
             :|:...:..||   :.....|.:..|.||...|.|...:..:        .:|.:|....|.|.
Mouse   169 EKKASENKSFDIFCDVGHMALDTLMKCTFGKGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHN 233

  Fly   220 -------PIGIAFINSFQNLARRLHMKITLEEAEHFFLRIVRETVAF----REKNNI---RRNDF 270
                   |.|..|:.:.|         |..:..:|    ::|:..|.    :|:..:   |..||
Mouse   234 DFIYWLTPHGRRFLRACQ---------IAHDHTDH----VIRQRKAALQDEKEQKKLQERRHLDF 285

  Fly   271 MDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVR 335
            :|.|:.      .:.|||  :.|:..::.|:...|...|.:|:::.:.:.||.:|.:...|.|.|
Mouse   286 LDILLG------ARDESG--IKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCR 342

  Fly   336 KECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYE-VPGHPKYVIKKGM 399
            :|.:|::|. .....::.:..|.||...:.|..|||..:|.:.|:..:... |.|..   :..|.
Mouse   343 EEVREILGD-RDSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGRS---LPAGS 403

  Fly   400 PVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLA 464
            .:.:...|:||:..::.:|..|:|..||||.:..|....::||..|||||||.:|...:.:...|
Mouse   404 LISLHIYALHRNSAVWPDPEVFDPLRFSPENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTA 468

  Fly   465 LLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFL 499
            |.:.||:||. :.:.|||...:  .::.|:.||.|
Mouse   469 LCLLRFEFSP-DPSKIPIKVPQ--LILRSKNGIHL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	110/478 (23%)
Cyp4b1	NP_031849.1	CYP4B-like	67..501	CDD:410771	113/496 (23%)