Protein Alignment Cyp6a9 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 507
• Identity: 154/507 - (30%)
• Similarity: 255/507 - (50%)
• Gaps: 37/507 - (7%)

  Fly     6 VLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNKFRGTG 70
            :|||..:||   |.|....:...::.|.||..:|...:|::...|  :.|....:..:.|:   |
Mouse    13 MLLATSLVL---LYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYQ--KGFWECDIQCHKKY---G 69

  Fly    71 PFAGFYWFQRPGILVLDISLAKLILIKE-FNKFTDRGFYHNTEDDP---LSGQLFLLDGQKWKSM 131
            ...|.|..::|.:.:.|..:.|.:|:|| ::.||:|..:     .|   |...:.:.:.::||.:
Mouse    70 KMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRF-----GPVGILKKAISISENEEWKRI 129

  Fly   132 RSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFGIECS 196
            |:.||.|||||::|.|||.:.:.....:....|.:.:.....::||...::.|||...:||:...
Mouse   130 RALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSMDVITATSFGVNID 194

  Fly   197 SLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLA---RRLHMKITLEEAEHFFLRIVRETVA 258
            ||.:|:..|....::.:......|:.:: :..|..|.   ..|::.:...:...||...|.....
Mouse   195 SLNNPQDPFVEKIKKLLKFDIFDPLFLS-VTLFPFLTPVFDALNVSLFPRDVISFFTTSVERMKE 258

  Fly   259 FREKNNIR-RNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALY 322
            .|.|...: |.||:..:|:.:|....:|...    |:..|:.||:.:|..||:||:|:.:.||||
Mouse   259 NRMKEKEKQRVDFLQLMINSQNYKTKESHKA----LSDVEIVAQSVIFIFAGYETTSSALSFALY 319

  Fly   323 ELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEV 387
            .||.|.|:|.:::.|....:.. ....||:::..|.|||.|::||||||.:...|.|.|..|.|:
Mouse   320 LLAIHPDVQKKLQDEIDAALPN-KAPATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEI 383

  Fly   388 PGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVE---WLPFGDGPRNC 449
            .|   ..|.||..|:||..|:|:|.|.:..|..|.|:.||.   |.:||:.   :||||.|||||
Mouse   384 NG---LFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSK---KNQDSINPYMYLPFGSGPRNC 442

  Fly   450 IGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKV 501
            |||||..:..:..|..::..|....|::|.||:..||:. |:..|..:.|||
Mouse   443 IGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQG-LLQPENPLLLKV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	136/440 (31%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	137/445 (31%)