Protein Alignment Cyp6a9 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 514
• Identity: 162/514 - (31%)
• Similarity: 266/514 - (51%)
• Gaps: 50/514 - (9%)

  Fly     6 VLLAIVVVLVGYLLLKWRRALH-YWQNLDIPCEEPHILMGSLTGVQTSRSFSAIW---MDYYNKF 66
            |||||.:|    ||.::....| .::...||..:|...:|::...     :..:|   |:.|.|:
Mouse    13 VLLAISLV----LLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNY-----YKGLWKFDMECYKKY 68

  Fly    67 RGT-GPFAGFYWFQRPGILVLDISLAKLILIKE-FNKFTDRGFYHNTEDDP---LSGQLFLLDGQ 126
            ..| |.|.|    |.|.:.|.|....|.:|:|| |:.||:|     .:..|   :|..:.:....
Mouse    69 GKTWGLFDG----QTPLLAVTDPETIKNVLVKECFSVFTNR-----RDFGPVGIMSKAISISKDD 124

  Fly   127 KWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAF 191
            :||..|:.||.||||||:|.|||.:.:.|...::...|..:|...|.::|:|..::.|||.:.:|
Mouse   125 EWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVITSTSF 189

  Fly   192 GIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFI------NSFQNLARRLHMKITLEEAEHFFL 250
            |:...||.:||..|....::.:......|:..:.:      ..::.|...:..|.::|..:.|..
Mouse   190 GVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVD 254

  Fly   251 RIVRETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESGESVN---LTIEEMAAQAFVFFGAGFET 312
            |:....:..::|:.:   ||:..:::..|:      |.:.|:   |:..|:.||:.:|..||:||
Mouse   255 RMKESRLDSKQKHRV---DFLQLMMNSHNN------SKDKVSHKALSDMEITAQSIIFIFAGYET 310

  Fly   313 SSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVL 377
            :|:|:.|.|:.||.|.|||.:::.|..|.:.. ....||:::.:|.|||.|::||||||.:...|
Mouse   311 TSSTLSFTLHSLATHPDIQKKLQDEIDEALPN-KAPPTYDTVMEMEYLDMVLNETLRLYPIANRL 374

  Fly   378 NRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPF 442
            .|.|.:|.|:.|   ..|.||..|:||..|:|.|.:.::.|..|.|:.||.|.....|...:|||
Mouse   375 ERVCKKDVELNG---VYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVYLPF 436

  Fly   443 GDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKV 501
            |:|||||:||||..|..:..|..::..|.|..|::|.||:..|::. |:..|..|.|||
Mouse   437 GNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQG-LLQPEKPIVLKV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	141/443 (32%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	143/448 (32%)