Protein Alignment Cyp6a9 and cyp4b1.3

DIOPT Version :10

• Sequence 1: NP_523748.2
• Gene: Cyp6a9 / 36663
• FlyBaseID: FBgn0013771
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_002931492.1
• Gene: cyp4b1.3 / 100487918
• XenbaseID: XB-GENE-980014
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 541
• Identity: 119/541 - (21%)
• Similarity: 227/541 - (41%)
• Gaps: 88/541 - (16%)

  Fly     2 GVYSVLLAIVVVLVGY--LLLKWRRALHYWQNLDIPCEEPHILMGSLT-----GVQTSRSFSAIW 59
            |.::.||.::::|:..  |.::|:......||  .|....|.|.|:..     |....|..  :|
 Frog    22 GQFAALLCLILLLLKACGLFIRWKSLKDALQN--FPGPPKHWLYGNANQFRNDGTDMDRIL--LW 82

  Fly    60 MDYYNKFRGTGPFAGFYWFQR--PGILVLDISLAKLILIKEFNKFTDRGFYHNTEDD---PLSGQ 119
            .:.|       |.|...|..:  ..:::.:...||....:...| |..|:      |   |..|:
 Frog    83 ANKY-------PKAFPLWVGQFFASLVITNPEYAKAAFARSDPK-TPTGY------DFLIPWIGK 133

  Fly   120 -LFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTT 183
             |.:|.|..|...|..|:..|....:|.....:.......::.:.....|...||:...::..|.
 Frog   134 GLLVLSGDTWFQHRRLLTPGFHYDVLKPYAKLISDSTKVMLDKWVPFSNKGEPVELFHHVSLMTL 198

  Fly   184 DVIGTCAFGIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKITLEEAEHF 248
            |.|..|||....:...|.:..:    .:|:::       ::::...:......|..:....:.|.
 Frog   199 DSIMKCAFSYHSNCQTDNDNSY----TKAVYD-------LSYLTHHRARTFPYHNNLIYYLSPHG 252

  Fly   249 FL-----RIV----------RETV-----AFREKNNIRRNDFMDQLIDLKNSPLTKSESGESVNL 293
            ||     ||.          |:|:     .|.:....|..||:|.|:      ..:.|:|:  .|
 Frog   253 FLFRKACRIAHQHTDKVIKQRKTLLQNKEEFEKVKQKRHPDFLDILL------CARDENGK--GL 309

  Fly   294 TIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMV 358
            :.|::.|:...|...|.:|:::.:.:.||.:|::.:.|.:.|:|.::|:|: .....:|.:..:.
 Frog   310 SDEDLRAEVDTFMFEGHDTTASGISWILYCMAKYPEHQQKCREEIRDVLGE-KESFEWEDLNKIP 373

  Fly   359 YLDQVISETLRLYTVLPVLNREC------LEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYAN 417
            |....|.|:||||..:|.::||.      .:...:|.        |..:.|....:||:..::.:
 Frog   374 YTTMCIKESLRLYPPVPAVSRELNKPITFSDGRSLPA--------GSVIFINIFCIHRNPTVWKD 430

  Fly   418 PNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPI 482
            |..|:|..||.|...:|.|..::||..|||||||..|...:.:..:||.:||::.|. :.:..|:
 Frog   431 PEVFDPLRFSSENSSKRHSHAFVPFAAGPRNCIGQNFAMNELKVAVALTLNRYELSP-DLSKAPL 494

  Fly   483 VYSKKTFLISSETGIFLKVER 503
              .....::.|:.||.:.:::
 Frog   495 --KSPQLVLRSKNGIHVYLKK 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a9	NP_523748.2	CYP6-like	68..498	CDD:410679	102/461 (22%)
cyp4b1.3	XP_002931492.1	CYP4B-like	76..510	CDD:410771	106/480 (22%)