Protein Alignment Cyp6a19 and DIT2

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 106/515 - (20%)
• Similarity: 196/515 - (38%)
• Gaps: 118/515 - (22%)

  Fly    35 PPNIPLGNTGELWRTMPLAGI------------LKRTYLKFRKQTDGPFAGFYLYAMKYIVITDV 87
            |.|||         |:|...:            |...|::...:..|. ..|:..:...|:::..
Yeast    30 PKNIP---------TIPFYVVFLPVIFPIDQTELYDLYIRESMEKYGA-VKFFFGSRWNILVSRS 84

  Fly    88 DFVKTVLIRDFDKFHDRGVYHNEKDDPLT-------NNLATIEGQKWKNLRQKLTH--------- 136
            :::..: .:|.|.|...|   |:|..|.:       :|:.:..|..|:|.|..:|:
Yeast    85 EYLAQI-FKDEDTFAKSG---NQKKIPYSALAAYTGDNVISAYGAVWRNYRNAVTNGLQHFDDAP 145

  Fly   137 TFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDP 201
            .|.:||:             :..::..::.....::.:..:..|...|.|...|.|....:|...
Yeast   146 IFKNAKI-------------LCTLIKNRLLEGQTSIPMGPLSQRMALDNISQVALGFDFGALTHE 197

  Fly   202 KAEFVQMGYSALRERRHGW-----LVDLLIFGMPKLAVK--LGFQFLLPSVQKFYMKIVQDTI-- 257
            |..|.:......::..|.:     .:|:|.....|.|.|  :.|:.||       :|.|||.:
Yeast   198 KNAFHEHLIRIKKQIFHPFFLTFPFLDVLPIPSRKKAFKDVVSFRELL-------VKRVQDELVN 255

  Fly   258 DYRMKRKV-TRNDFM----DTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFT 317
            :|:.::.. ..:|.:    :.:||.||..|               ...:..:||.|........:
Yeast   256 NYKFEQTTFAASDLIRAHNNEIIDYKQLTD---------------NIVIILVAGHENPQLLFNSS 305

  Fly   318 LYELA-CNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKP 381
            ||.|| .:.:.|:|||.|:       ||..:...:.||..:...:.|.:|.:|.::.:....|..
Yeast   306 LYLLAKYSNEWQEKLRKEV-------NGITDPKGLADLPLLNAFLFEVVRMYPPLSTIINRCTTK 363

  Fly   382 YQHSNPKYFIEAGTGVLVSTLGIHHDPEFY-PEPEKFIPERF--DEEQVKK-----RPTCAFLPF 438
            ......:..|..|..|..:..|..|||:.: ...:.|.|||:  |.|.::|     :..||...|
Yeast   364 TCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGF 428

  Fly   439 GAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPK-----------TPVPMKYTINNLLL 487
            ..|.|.|:|.:....::.|.||.::..||:.|.|:           .|:.:|...|..::
Yeast   429 HGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLKLKFNENIM 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	98/471 (21%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	97/466 (21%)