DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a19 and CYP715A1

DIOPT Version :9

Sequence 1:	NP_611001.2	Gene:	Cyp6a19 / 36662	FlyBaseID:	FBgn0033979	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_200053.2	Gene:	CYP715A1 / 835316	AraportID:	AT5G52400	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	112/501 - (22%)
Similarity:	206/501 - (41%)	Gaps:	56/501 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ILLGLVVGVLTLVAW-WVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGIL-----KRTYL 61
            :::.|:...|.|..| |.::.....:..|.....|:.|.||..:: :.:.:|.::     ..|.:
plant    19 VVICLMFLKLFLRCWIWPVRAQKKLRGNGFVGPAPSFPFGNLNDM-KKLKMASVVVDNSKSSTII 82

  Fly    62 KFR------------KQTDGPFAGFYLYAMKYIVITDVDFV----KTVLIRDFDKFHDRGVYHNE 110
            ...            :|..|....::|....::.:.|.:|:    |.||.:.:.|   ..|:..:
plant    83 NHDIHSIALPHFARWQQEYGKVFVYWLGIEPFVYVADPEFLSVMSKGVLGKSWGK---PNVFKKD 144

  Fly   111 KDDPLTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVT 175
            ::......|..:||..|...|..:|..|....:|.|.:.::.....|:.....:|:|.:...::.
plant   145 REPMFGTGLVMVEGDDWTRHRHIITPAFAPLNLKVMTNMMVESVSNMLDRWGIQINSGNPEFDME 209

  Fly   176 DIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQF 240
            ..:.....::|...:||:...:           |...|:..|   .|...:|...:. |.:.|..
plant   210 SEIIGTAGEIIAKTSFGVTGEN-----------GTQVLKNLR---AVQFALFNSNRY-VGVPFSN 259

  Fly   241 LLPSVQKFYMKIVQDTID-----YRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAF 300
            :|...|....|.:...||     :..|||::..:..|...|:.....|.|::......|:..:..
plant   260 ILSYKQTVKAKGLGHEIDGLLLSFINKRKISLAEGDDQGHDLLGMLLKADQKGNFTAKELVDECK 324

  Fly   301 VFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESL 365
            .||.||.|..:..:.:|...||.:.:.||.:|.||..|:.  :.|:||:.:..|..|..|:||.|
plant   325 TFFFAGHETTALALTWTFMLLAIHPEWQDTIREEIREVIG--DSKIEYNKLAGLKKMSWVMNEVL 387

  Fly   366 RKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFY-PEPEKFIPERFD---EEQ 426
            |.:|...:..|.|....:.:.  ..|..||.:.:..:.:|||.|.: .:..:|.|||||   ...
plant   388 RLYPPAPNAQRQARNDIEVNG--RVIPNGTNIWIDVVAMHHDVELWGDDVNEFKPERFDGNLHGG 450

  Fly   427 VKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHP 472
            .|.:  ..::|||.|.|.|||.....|:..|.|:|::..|...:.|
plant   451 CKNK--MGYMPFGFGGRMCIGRNLTTMEYKIVLSLVLSRFEISVSP 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	106/471 (23%)
CYP715A1	NP_200053.2	p450	16..519	CDD:299894	112/501 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810