DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a19 and CYP72A10

DIOPT Version :9

Sequence 1:	NP_611001.2	Gene:	Cyp6a19 / 36662	FlyBaseID:	FBgn0033979	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_188082.2	Gene:	CYP72A10 / 820692	AraportID:	AT3G14640	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	133/552 - (24%)
Similarity:	230/552 - (41%)	Gaps:	112/552 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VLTLVAWWVLQNY-----------TYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYLKFR 64
            |:.:|:|||.:..           :|.:|:|:...|             ..||.|.|||......
plant    35 VVVVVSWWVWRTLQWVWFKPKMLESYLRRQGLAGTP-------------YTPLIGDLKRNVNMLT 86

  Fly    65 KQTDGP--------------------------FAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHD 103
            :.|..|                          |.  :|.....|.|.|.:.:|.|    |:|.:|
plant    87 EATSKPIKLTEDITPRVLPHPFQMLKTHGRTFFT--WLGPKPTITIMDPELIKEV----FNKVYD 145

  Fly   104 RGVYHNEKDDPLTNNLAT----IEGQKWKNLRQKLTHTFTSAKMKSM----FSTVLNVGDEMIRV 160
               |...:...|...:||    .:|.||...|:.:...|...|:|:|    ..:..:|..|..::
plant   146 ---YPKAQTFLLGRLIATGIINYDGDKWAKHRRIINPAFHIEKIKNMVPAFHQSCSDVVGEWSKL 207

  Fly   161 VDEKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLL 225
            |.:|.|||.: ::|...:...|.|||...|||   :|.::.:..|          .....||.|:
plant   208 VSDKGSSSCE-VDVWPWLVSMTGDVISRTAFG---SSYKEGQRIF----------ELQAELVHLI 258

  Fly   226 IFGMPKLAVKLGFQFLLPSVQKFYMK--------IVQDTIDYRMK-----RKVTRNDFMDTLIDM 277
            :....|:.:. |::: ||:.....||        |::..::.|::     :....:|.:..|::.
plant   259 LQAFWKVYIP-GYRY-LPTKSNRRMKAAAREIQVILKGIVNKRLRAREAGKAAPNDDLLGILLES 321

  Fly   278 KQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERY 342
            .....||   ||::..:|..:..:|:.||.|..|..:.:.:..|:.:||.|.:.|.|:..|.
plant   322 NLGQAKG---NGMSTEDVMEECKLFYFAGQETTSVLLVWAMVLLSHHQDWQARAREEVKQVF--- 380

  Fly   343 NGKLEYDS--MQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIH 405
             |..|.|:  :..|..|..::.|.||.:|.|.||.|...|..:..:  ..:.||..:.:..:.:.
plant   381 -GDKEPDTECLSQLKVMTMILYEVLRLYPPVTHLTRAIDKEMKLGD--LTLPAGVHISLPIMLVQ 442

  Fly   406 HDPEFY-PEPEKFIPERFDEEQVK-KRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRF 468
            .||..: .:..:|.||||.:...| .:...:|.||..|||.|||..|..::..:.:||::..|.|
plant   443 RDPMLWGTDAAEFKPERFKDGLSKATKSQVSFFPFAWGPRICIGQNFAMLEAKMAMALILQTFTF 507

  Fly   469 ELHPKTPVPMKYTINNLLLGSEGGIHLNITKV 500
            ||.| :.|....|:  :.:..:.|.||.:.|:
plant   508 ELSP-SYVHAPQTV--VTIHPQFGAHLILRKL 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	122/513 (24%)
CYP72A10	NP_188082.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810