DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a19 and CYP72A8

DIOPT Version :9

Sequence 1:	NP_611001.2	Gene:	Cyp6a19 / 36662	FlyBaseID:	FBgn0033979	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_188080.1	Gene:	CYP72A8 / 820690	AraportID:	AT3G14620	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	145/537 - (27%)
Similarity:	230/537 - (42%)	Gaps:	95/537 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AILLGLVVGVLTLVAWWV-----------LQNYTYWKRRGIPHDP------------------PN 37
            |:.:...|.|:|.|..|:           .:|..|.||:|:...|                  .:
plant     8 AVAVAAAVVVVTTVTVWIWKGLNVAWLRPKKNEAYLKRQGLSGTPFTFLVGDIKREASMVEQEKS 72

  Fly    38 IPLGNTGE-LWRTMPLAGILKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKF 101
            .|:..|.: ..|.|||.....:.:.|......||.|.        :::|..:.:|.||.|.:| |
plant    73 RPINLTDDYTHRVMPLIQQTVKDHGKTSYMWMGPIAS--------VIVTKPEHIKDVLNRVYD-F 128

  Fly   102 HDRGVYHNEKDDPLTNNLAT----IEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMI---- 158
            ....|:      |:....||    .||:||...|:.:..:|...|:|.|.........|||
plant   129 PKPPVH------PIVELFATGVALYEGEKWSKHRKIINPSFHLEKLKIMIPAFYESCSEMISKWE 187

  Fly   159 RVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVD 223
            ::|.|:  .||..::|...:...|||||...|||   :|..:.|..|      .|:|.:...::.
plant   188 KLVTEQ--GSSNEIDVWPYLGDLTSDVISRTAFG---SSYEEGKRIF------ELQEEQGRRVLK 241

  Fly   224 LLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQDTIDYR-----MKR-------KVTRNDFMDTLID 276
            .|     :||...|.:| ||:.....|:.:...:..|     |||       :..:||.:..|::
plant   242 AL-----ELAFIPGMRF-LPTKNNLRMRQINKEVKSRLREIIMKRQRGMDTGEAPKNDLLGILLE 300

  Fly   277 MKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLER 341
            .    :.||  :|::..:|..:..:|..||.|..:..:.:|:..|:.:|..||:.|.||..|:.:
plant   301 S----NSGD--HGMSIEDVVEECRLFHFAGQETTAVLLVWTMIMLSHHQKWQDQAREEILKVIGK 359

  Fly   342 YNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHH 406
             |.|..:|::..|..|..::||.||.:|....|.|...|..: ......:..|..|::..|.:|.
plant   360 -NNKPNFDALSRLKTMSMILNEVLRLYPPGILLGRTVEKETK-LGEDMTLPGGAQVVIPVLMVHR 422

  Fly   407 DPEFYPEP-EKFIPERF-DEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFE 469
            |||.:.|. .:|.|||| |......:...:|||||.|||.|.|..|..|:..:.|.|::..|.||
plant   423 DPELWGEDVHEFNPERFADGISKATKNQVSFLPFGWGPRFCPGQNFALMEAKMALVLILQRFSFE 487

  Fly   470 LHPK-TPVPMKYTINNL 485
            |.|. |..|  :|:..|
plant   488 LSPSYTHAP--HTVLTL 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	134/496 (27%)
CYP72A8	NP_188080.1	p450	26..515	CDD:299894	139/519 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900