Protein Alignment Cyp6a19 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 458
• Identity: 128/458 - (27%)
• Similarity: 222/458 - (48%)
• Gaps: 62/458 - (13%)

  Fly    69 GPF-AGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDP-LTNNLATIEGQKWKNLR 131
            ||| |.||:|        |.|:.|..|.|...|..    |.::...| :...|..::|.:|...|
Mouse    85 GPFQAFFYIY--------DPDYAKIFLSRTDPKMQ----YLHQLLTPCIGRGLLNLDGPRWFQHR 137

  Fly   132 QKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCN 196
            ..||..|....:|....|:.:....|:...::..::...|:||.:.::..|.|:|..||||.:.|
Mouse   138 CLLTPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQETN 202

  Fly   197 SLRD------PKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLG--FQFLLPSVQKFYMKIV 253
            ...:      .||.| ::|........:.|....:||   ||:.| |  ||.|...:.::..||:
Mouse   203 CQINGTYESYVKATF-ELGEIISSRLYNFWHHHDIIF---KLSPK-GHCFQELGKVIHQYTEKII 262

  Fly   254 QDTIDYRMKRKVTRND-----------FMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGF 307
            ||      ::|:.:|.           |:|.::..     :.:.|...:..::.|:...|..||.
Mouse   263 QD------RKKILKNQVKQDDTQTSQIFLDIVLSA-----QAEDERAFSDADLRAEVNTFMWAGH 316

  Fly   308 EAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVA 372
            :|.:.::.:.||.||.|.:.||:.|.||.|:|.. ...:.::.:.::.|....|.|:||..|.|.
Mouse   317 DASAASISWLLYCLALNPEHQDRCRTEIRSILGD-GSSITWEQLDEMSYTTMCIKETLRLIPPVP 380

  Fly   373 HLARIATKPYQ----HSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTC 433
            .::|..:||..    ||.|     ||..|::|..|:||:|..:.:|:.|.|.||.:|...:|..|
Mouse   381 SISRELSKPLTLPDGHSLP-----AGMTVVLSIWGLHHNPAVWNDPKVFDPLRFTKENSDQRHPC 440

  Fly   434 AFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLNIT 498
            |||||.:|||||||.:|..:::.:.:||::  ..|::.|....|..:: ::.:|..:.||:|::.
Mouse   441 AFLPFSSGPRNCIGQQFAMLELKVAIALIL--LHFQVAPDLTRPPAFS-SHTVLRPKHGIYLHLK 502

  Fly   499 KVV 501
            |::
Mouse   503 KLL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	125/449 (28%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	126/451 (28%)