Protein Alignment Cyp6a19 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 520
• Identity: 143/520 - (27%)
• Similarity: 242/520 - (46%)
• Gaps: 49/520 - (9%)

  Fly     4 LLGLVVGVLTLVAWWVLQNYTYWKR----RGIPHDPP-NIPLGNTGELWRTMPLAGILKRTYLKF 63
            ||.|:.|...|:|:.:...|..::.    |..|..|. |..||:.|.:..:.  .|:|   |::.
Mouse    20 LLLLLAGASCLLAYILTPIYGVFENSLRLRCFPQPPKRNWILGHLGLIQSSE--EGLL---YIQS 79

  Fly    64 RKQTDGPFAGFYLYAMKYIV-ITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATIEGQKW 127
            ..:|......:::..:..:: |....|:|.|::..........|::......|.:.|....|.||
Mouse    80 LVRTFRDACCWWVGPLHPVIRIFHPAFIKPVVLAPALVAPKDTVFYRFLKPWLGDGLLMSTGDKW 144

  Fly   128 KNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISS-SSQTLEVTDIVSRFTSDVIGICAF 191
            ...|:.||..|....:|. :..|.|....::....::::| .|..|.:.:.:|..|.|.:..|.|
Mouse   145 SRHRRMLTPAFHFNILKP-YVKVFNDSTNIMHAKWQRLASKGSAYLNMFEHISLMTLDSLQKCVF 208

  Fly   192 GLKCNSLRDPKAEFVQ--MGYSALRERRHGWL---VDLLIF----GMP-KLAVKLGFQFLLPSVQ 246
            ....|....| :|::.  :..|.|..|||..|   |||..:    ||. :.|.:|...|....::
Mouse   209 SFDSNCQEKP-SEYITAILELSTLVARRHQRLLLHVDLFYYLTHDGMRFRKACRLVHDFTDAVIR 272

  Fly   247 KFYMKIV-QDTID-YRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEA 309
            :....:: |..:| .:.|.|....||:|.|:..|.::.|     .|:..::.|:|..|...|.:.
Mouse   273 ERRRTLLDQGGVDVLKAKAKAKTLDFIDVLLLSKDEHGK-----ALSDEDIRAEADTFMFGGHDT 332

  Fly   310 GSTTMGFTLYELACNQDVQDKLRAEIDSVL-ERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAH 373
            .::.:.:.||.||.:.:.|::.|.|:..:| :|...::|:|.:..|.::...|.||||.||.|..
Mouse   333 TASGLSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTA 397

  Fly   374 LARIATK----PYQHSNPKYFIEAGTGVL--VSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPT 432
            ::|..|:    |.....||       ||:  :|..|.||:|..:|:||.:.|.|||.:.||.|..
Mouse   398 ISRCCTQDIVLPDGRVIPK-------GVISRISIFGTHHNPAVWPDPEVYDPFRFDADNVKGRSP 455

  Fly   433 CAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLNI 497
            .||:||.||||||||..|...::.:.|||.:  .||.:.|....|.:..  .|:|.:|||:.|.:
Mouse   456 LAFIPFSAGPRNCIGQTFAMSEMKVALALTL--LRFRVLPDDKEPRRKP--ELILRAEGGLWLKV 516

  Fly   498  497
            Mouse   517  516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	125/447 (28%)
Cyp4f18	NP_077764.2	CYP4F	74..515	CDD:410772	127/461 (28%)