Protein Alignment Cyp6a19 and Cyp4f14

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_071879.1
• Gene: Cyp4f14 / 64385
• MGIID: 1927669
• Length: 524
• Species: Mus musculus
• Alignment Length: 536
• Identity: 147/536 - (27%)
• Similarity: 239/536 - (44%)
• Gaps: 90/536 - (16%)

  Fly    11 VLTLVAWWVL-----------QNYTYWKRRGIPHDPP-NIPLGNTG----------ELWRTMPLA 53
            :|.|.|.|:|           :||.:  ..|.|..|. |..:|:.|          ||.|   |.
Mouse    22 LLLLGASWILARILIQIYAAYRNYRH--LHGFPQPPKRNWLMGHVGMVTPTEQGLKELTR---LV 81

  Fly    54 GILKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVL-------IRDFDKFHDRGVYHNEK 111
            |...:.:|.:    .||.       :..|.:...|.|:::|       ::|.       ::::..
Mouse    82 GTYPQGFLMW----IGPM-------VPVITLCHSDIVRSILNASAAVALKDV-------IFYSIL 128

  Fly   112 DDPLTNNLATIEGQKWKNLRQKLTHTFTSAKMK---SMFSTVLNVGDEMIRVVDEKISSSSQTLE 173
            ...|.:.|....|.||...|:.||..|....:|   .:|:...|:   |.......||..|..|:
Mouse   129 KPWLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNI---MHAKWQRLISDGSARLD 190

  Fly   174 VTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQ--MGYSALRERRHG---WLVDLLIFGMP--- 230
            :.:.||..|.|.:..|.|....| .::..:|::.  :..|||..:||.   ..:|||....|
Mouse   191 MFEHVSLMTLDSLQKCVFSFDSN-CQEKSSEYIAAILELSALVAKRHQQPLMFMDLLYNLTPDGM 254

  Fly   231 --KLAVKLGFQFLLPSVQKFYMKIVQDTIDYRMKRKVTRN--DFMDTLIDMKQQYDKGDKENGLA 291
              :.|..:..:|....:::.:..:....:|..:|.|....  ||:|.|:..|   |:..||  |:
Mouse   255 RFRKACNVVHEFTDAVIRERHRTLPDQGLDDFLKSKAKSKTLDFIDVLLLSK---DEDGKE--LS 314

  Fly   292 FNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLE-RYNGKLEYDSMQDLF 355
            ..::.|:|..|...|.:..::.:.:.||.||.:.:.|::.|.|:..:|. |...::|:|.:..|.
Mouse   315 DEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGREPEEIEWDDLAQLP 379

  Fly   356 YMEKVINESLRKHPVVAHLARIATK----PYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEK 416
            ::...|.||||.||.|..::|..|:    |...:.||     |...|:|..||||:|..:|:||.
Mouse   380 FLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPK-----GIICLISIFGIHHNPSVWPDPEV 439

  Fly   417 FIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYT 481
            :.|.|||.|.:|.....||:||.||||||||..|...::.:.|||.:  .||.|.|....|.:..
Mouse   440 YDPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTL--LRFRLLPDDKEPRRQP 502

  Fly   482 INNLLLGSEGGIHLNI 497
              .|:|.:|||:.|.:
Mouse   503 --ELILRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	127/453 (28%)
Cyp4f14	NP_071879.1	CYP4F	74..515	CDD:410772	133/479 (28%)