Protein Alignment Cyp6a19 and Cyp4f40

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_006524820.1
• Gene: Cyp4f40 / 631304
• MGIID: 3645508
• Length: 551
• Species: Mus musculus
• Alignment Length: 543
• Identity: 138/543 - (25%)
• Similarity: 234/543 - (43%)
• Gaps: 95/543 - (17%)

  Fly     4 LLGLVVGVLTLVAWWVLQNYTYWKR----RGIPHDP-PNIPLGNTG-------------ELWRTM 50
            ||..:||:...:|.::.|.||.:.:    .|.|..| .|...|:.|             ||..|.
Mouse    47 LLFFLVGISWFLARFLTQLYTLYAKCQRLCGFPQPPKKNWFWGHLGMSPPTEEGMKQVTELVTTY 111

  Fly    51 PLAGILKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPL 115
            | .|.:  |:|       ||.       :..|.:...|.:::||...........::::.....|
Mouse   112 P-QGFM--TWL-------GPI-------VPLITLCHPDIIRSVLSASAAVAPKDDIFYSFLKPWL 159

  Fly   116 TNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQT-LEVTDIVS 179
            .:.|....|.||...|:.||..|....:|. :..:.|....::.....:::|...| |.:.:.:|
Mouse   160 GDGLLVSAGDKWNRHRRMLTPAFHFNILKP-YVKIFNDSTNIMHAKWLRLASGGSTRLNMFENIS 223

  Fly   180 RFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLL-- 242
            ..|.|.:..|.|....|....| ::::    :|:.|             :..||||...|.|:
Mouse   224 LMTLDTLQKCVFSFNSNCQEKP-SQYI----AAILE-------------LSTLAVKRNEQLLMHV 270

  Fly   243 -------PSVQKFY--MKIVQDTID------------------YRMKRKVTRNDFMDTLIDMKQQ 280
                   |...:||  .::|.|..|                  .:.|.|....||:|.|:..|
Mouse   271 DLLYRLTPDGMRFYKACRLVHDFTDAVIQERRRTLLKHGGDDIIKAKAKSKTLDFIDVLLLTK-- 333

  Fly   281 YDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVL-ERYNG 344
             |:..||  |:..::.|:|..|...|.:..::.:.:.||.||.:.:.|::.|.|:..:| :|...
Mouse   334 -DEDGKE--LSDEDIRAEADTFMFRGHDTTASGLSWILYNLARHPEHQERCRQEVQELLRDRDPK 395

  Fly   345 KLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPE 409
            ::|:|.:..|.::...|.||||.||.|..::|..|:.....:.: .|..|...:::..|.||:|.
Mouse   396 EIEWDDLAQLPFLTMCIKESLRLHPPVTMVSRCCTQDISLPDGR-IIPKGVICIINIFGTHHNPT 459

  Fly   410 FYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKT 474
            .:.:||.:.|.|||.|.::.|...:|:||.||||||||..|...::.:.|||.:  .||.:.|..
Mouse   460 VWRDPEVYDPFRFDPENIQARSPLSFIPFSAGPRNCIGQTFAMSEMKVALALTL--LRFRILPDD 522

  Fly   475 PVPMKYTINNLLLGSEGGIHLNI 497
            ..|.:..  .|:|.:|||:.|.:
Mouse   523 KEPRRKP--ELILRAEGGLWLRV 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	116/457 (25%)
Cyp4f40	XP_006524820.1	CYP4F	101..542	CDD:410772	123/486 (25%)