Protein Alignment Cyp6a19 and Cyp3a57

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 503
• Identity: 161/503 - (32%)
• Similarity: 255/503 - (50%)
• Gaps: 70/503 - (13%)

  Fly     8 VVGVLTLVAWWVLQNYTY--WKRRGIPHDPPNIPL-GNTGELWRTMPLAGILK---RTYLKFRKQ 66
            |:.|.:||.:::...|::  :|:.||| .|..:|| ||....     |.|:.|   ..|.|:
Mouse    13 VLLVTSLVFFYIYGTYSHGLFKKLGIP-GPKPLPLFGNIINY-----LDGMWKFDDDCYKKY--- 68

  Fly    67 TDGPFAGFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDRGVYHNEKDDP---LTNNLATIEGQKW 127
              |...|||......:.|.|.:.:|.||::: :..|.:|..:     .|   |..::...|.::|
Mouse    69 --GKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPF-----GPVGFLKKSITISEDEEW 126

  Fly   128 KNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVV---DEKISSSSQTLEVTDIVSRFTSDVIGIC 189
            |.||..|:.||||:|:|.||..:...||.::|.:   :||    .:.:.:.||...::.|||...
Mouse   127 KRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEK----EEPINMKDIFGAYSMDVITGT 187

  Fly   190 AFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQ-------- 246
            :.|:..:||.:|:..|||.....|:.:          |..|.|...:.|.||.|..:
Mouse   188 SCGVNIDSLNNPQDPFVQKIKKILKFK----------FFDPFLLSVVLFPFLTPIYEMLNLSIFP 242

  Fly   247 --------KFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKE-NGLAFNEVAAQAFVF 302
                    ||..|:.:|.:||..|.:|   ||:..:  |..|..||.:. ..|:..|:|||..:|
Mouse   243 RQSMNFFKKFVKKMKKDRLDYNQKNRV---DFLQLM--MNTQNSKGQESLKALSDLEMAAQTLIF 302

  Fly   303 FLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRK 367
            ...|::..||::.|.:||||.:.|||.||:.|||..|.. ...:.||::.|:.|::.|:|||||.
Mouse   303 IFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRALPN-KAPVTYDALMDMEYLDMVVNESLRL 366

  Fly   368 HPVVAHLARIATKPYQ-HSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRP 431
            :|||:.:.|.:.|..: |.   .||..||.|::....:|.|||::||||.|.||||.:|......
Mouse   367 YPVVSRIDRFSKKDVEIHG---VFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNID 428

  Fly   432 TCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMK 479
            ...::|||.|||||||:||..:.|.:.:..::.||..:...:|.:|:|
Mouse   429 PYIYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVK 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	153/477 (32%)
Cyp3a57	NP_001093650.1	p450	39..493	CDD:278495	153/477 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720