Protein Alignment Cyp6a19 and Cyp4f1

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_062569.2
• Gene: Cyp4f1 / 56266
• RGDID: 70926
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 148/544 - (27%)
• Similarity: 236/544 - (43%)
• Gaps: 106/544 - (19%)

  Fly    11 VLTLVAWWVLQN--------YTYWKR-RGIPHDPP-NIPLGNTG----------ELWRTMPLAGI 55
            :|...|.|:|..        |..::| ||.|..|. |..:|:.|          ||.|   |.|.
  Rat    22 LLLFGASWILAQILTQIYAAYRNFRRLRGFPQPPKRNWLMGHVGMVTPTEQGLKELTR---LVGT 83

  Fly    56 LKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVL-------IRDFDKFHDRGVYHNEKDD 113
            ..:.:|.:    .||.       :..|.:...|.|:::|       ::|.       :::.....
  Rat    84 YPQGFLMW----IGPM-------VPVITLCHSDIVRSILNASAAVALKDV-------IFYTILKP 130

  Fly   114 PLTNNLATIEGQKWKNLRQKLTHTFTSAKMK---SMFSTVLNVGDEMIRVVDEKISSSSQTLEVT 175
            .|.:.|....|.||...|:.||..|....:|   .:|:...|:   |.......||..|..|::.
  Rat   131 WLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNI---MHAKWKRLISEGSSRLDMF 192

  Fly   176 DIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQ--MGYSALRERRHGWLVDLLIFGMPKLAVKLGF 238
            :.||..|.|.:..|.|....| .::..:|::.  :..|||..:||         ..|.|.:.|.:
  Rat   193 EHVSLMTLDSLQKCVFSFDSN-CQEKSSEYIAAILELSALVAKRH---------QQPLLFMDLLY 247

  Fly   239 QFLLPSVQKFY--MKIVQDTID------------------YRMKRKVTRNDFMDTLIDMKQQYDK 283
            . |.|...:|:  ..:|.:..|                  .:.|.|....||:|.|:..|   |:
  Rat   248 N-LTPDGMRFHKACNLVHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTK---DE 308

  Fly   284 GDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVL-ERYNGKLE 347
            ..||  |:..::.|:|..|...|.:..::.:.:.||.||.:.:.|::.|.|:..:| :|...::|
  Rat   309 DGKE--LSDEDIRAEADTFMFEGHDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRDPEEIE 371

  Fly   348 YDSMQDLFYMEKVINESLRKHPVVAHLARIATK----PYQHSNPKYFIEAGTGVLVSTLGIHHDP 408
            :|.:..|.::...|.||||.||.|..::|..|:    |...:.||     |...|:|..||||:|
  Rat   372 WDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPK-----GIICLISIFGIHHNP 431

  Fly   409 EFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPK 473
            ..:|:||.:.|.|||.|.:|.....||:||.||||||||..|...::.:.|||.:  .||.|.|.
  Rat   432 SVWPDPEVYNPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTL--LRFRLLPD 494

  Fly   474 TPVPMKYTINNLLLGSEGGIHLNI 497
            ...|.:..  .|:|.:|||:.|.:
  Rat   495 DKEPRRQP--ELILRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	128/463 (28%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	134/489 (27%)