Protein Alignment Cyp6a19 and cyp4v2a

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001071070.1
• Gene: cyp4v2a / 558851
• ZFINID: ZDB-GENE-061103-601
• Length: 513
• Species: Danio rerio
• Alignment Length: 558
• Identity: 142/558 - (25%)
• Similarity: 225/558 - (40%)
• Gaps: 122/558 - (21%)

  Fly     9 VGVLT--------------LVAWWVLQNYTY-WKR-RGIPHDPPNIPLGNTGELWRTMPLAGILK 57
            |||.|              .:.:.:|::|.: ||. :.||      .:||      |.|..|
Zfish     5 VGVYTYGFVAASVCVICFAYITYQLLKSYLHKWKELKPIP------GIGN------TFPFIG--- 54

  Fly    58 RTYLKFRKQTD--------------GPFAGFYLYAMKYIVITDVDFVKTVLIR--DFDKFHDRGV 106
             ..|:|:...|              .|....::..:.::::...:.|:|||..  ..||.:....
Zfish    55 -NALQFKSNGDFFLQLVGYTTEFQNSPLLKIWIGPIPFLILFHAETVETVLNNPVHIDKAYAYQF 118

  Fly   107 YHNEKDDP-LTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISS--- 167
            .|     | |...|.|..|.||:..|:.||.||..    |:.:..|.|.:|...|:.||:..
Zfish   119 LH-----PWLGTGLLTSTGDKWRRRRKMLTPTFHF----SILTEFLEVMNEQAEVLIEKLEKQAG 174

  Fly   168 -------SSQTLEVTDIVSRFTSDVIGIC--AFGLKCNSLRDPKAEFVQMGYS----ALRERRHG 219
                   |..||...||          ||  |.|.:..:..:..:|:|:..|.    ..|.:|..
Zfish   175 KGPFNCFSHITLCALDI----------ICETAMGKRIYAQSNYDSEYVRTVYRMSDIITRRQRMP 229

  Fly   220 WLVDLLIFGM--------PKLAVKLGFQFLLPSVQKFYMKIVQ-DTIDYRMKRKVTRNDFMDTLI 275
            |.....::..        ..|.:...|...:.:.:..|:..|: |:...:..||  |..|:|.|:
Zfish   230 WYWPDFVYNYVGEGREHNRSLKILHSFTESVINERAEYLSYVESDSESDQGMRK--RRAFLDMLL 292

  Fly   276 DMKQQYDKGDKENG--LAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSV 338
            ..|.       |:|  |...::..:...|...|.:..:..|.:.::.|..:.:||.|.:.|:..|
Zfish   293 KTKD-------EDGKMLTHKDIQEEVDTFMFEGHDTTAAAMNWAIHLLGSHPEVQRKAQQELFEV 350

  Fly   339 LERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLG 403
            .......:..:.::.|.|:|.||.||||..|.|...||......|.:..|  :..||.::|.|..
Zfish   351 FGESERPVNTEDLKKLRYLECVIKESLRLFPSVPFFARTICDDTQINGFK--VPKGTNIVVITYA 413

  Fly   404 IHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNF-- 466
            :|.||.|:|:||:|.||||..|....|...|::||.||.|||||.||..|:..:.||.::..|
Zfish   414 LHRDPRFFPDPEEFRPERFLPENCVGRHPYAYIPFSAGLRNCIGQRFAIMEEKVILAYILRYFNI 478

  Fly   467 -----RFELHPKTPVPMKYTINNLLLGSEGGIHLNITK 499
                 |.||.|         :..|:|..|.||.:.:.:
Zfish   479 VACQKREELRP---------LGELVLRPEQGIWITLER 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	124/477 (26%)
cyp4v2a	NP_001071070.1	cytochrome_P450	68..503	CDD:477761	124/473 (26%)