Protein Alignment Cyp6a19 and cyp26a1

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_012822016.1
• Gene: cyp26a1 / 548901
• XenbaseID: XB-GENE-855583
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 540
• Identity: 118/540 - (21%)
• Similarity: 206/540 - (38%)
• Gaps: 138/540 - (25%)

  Fly     8 VVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAG------ILKRTYLKFRKQ 66
            |:.:||....|  :.|...::.....:|  :|.|..|     :|..|      :.:|.:|:.:::
 Frog    18 VLLLLTAAKLW--EVYCLSRKDASCRNP--LPPGTMG-----LPFFGETLQMVLQRRKFLQVKRR 73

  Fly    67 TDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATIEGQKWKNLR 131
            ..|.....:|:....:.:|..:.|:.:|:.:
 Frog    74 KYGRIYKTHLFGSPTVRVTGAENVRQILLGE---------------------------------- 104

  Fly   132 QKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCN 196
                |...|....:...|:|..|         .:|:      :.|...::|..|| :.||.
 Frog   105 ----HKLVSVHWPASVRTILGAG---------CLSN------LHDSEHKYTKKVI-MQAFS---- 145

  Fly   197 SLRDPKAEFVQMGYSALRERRHGWLVD---LLIFG-----MPKLAVKL----------------- 236
              |:..|.:|.:....||...:.||..   :|::.     |.::|::|
 Frog   146 --REALANYVPLMEEELRRSVNLWLQSDSCVLVYPAIKRLMFRIAMRLLLGCDPQRLGREQEETL 208

  Fly   237 --GFQ------FLLPSVQKF--------YMKIVQDTIDYRMKRKVTR------NDFMDTLIDMKQ 279
              .|:      |.||....|        ...|:...|:..:|.|:.|      .|.:..|||..:
 Frog   209 LEAFEEMTRNLFSLPIDVPFSGLYRGLRARNIIHAQIEENIKEKLQREPDGQCRDALQLLIDHSR 273

  Fly   280 QYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDS--VLE-- 340
            :  .|:..|..|..|.|.: .:|...|..|.:.|...|.  ||.::||.:|:|.|::|  :|.
 Frog   274 R--TGEPVNLQALKESATE-LLFGGHGTTASAATSLTTF--LALHKDVLEKVRKELESQGLLSNK 333

  Fly   341 -RYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGI 404
             ....:|..:.:|.|.|...||.|:||..|.||...|:|.|.:..:.  |.|..|..|:.|....
 Frog   334 PEEKKELSIEVLQQLKYTSCVIKETLRLSPPVAGGFRVALKTFVLNG--YQIPKGWNVIYSIADT 396

  Fly   405 HHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFE 469
            |.:.|.:|:.::|.|:||............|:|||.|.|.|:|..|.::.:.:.:..|..|..:|
 Frog   397 HGEAELFPDKDEFNPDRFLTPLPGDSSRFGFIPFGGGVRCCVGKEFAKILLKVFIVELCRNCDWE 461

  Fly   470 LHPKTPV----PMKYTINNL 485
            |...:|.    |:...::||
 Frog   462 LLNGSPAMKTSPIICPVDNL 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	105/475 (22%)
cyp26a1	XP_012822016.1	cytochrome_P450	55..485	CDD:477761	108/494 (22%)