Protein Alignment Cyp6a19 and cyp3a4.2

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001015786.1
• Gene: cyp3a4.2 / 548503
• XenbaseID: XB-GENE-971750
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 147/509 - (28%)
• Similarity: 238/509 - (46%)
• Gaps: 75/509 - (14%)

  Fly     7 LVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYLKFRK---QTD 68
            |:..:|.|:..:.:..|.|:|:.|||...|             :|..|    |:|:|||   |.|
 Frog    14 LLAALLVLILLYGIWPYGYFKKMGIPGPTP-------------LPFIG----TFLEFRKGMVQFD 61

  Fly    69 -------GPFAGFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDR---GVYHNEKDDPLTNNLATI 122
                   |...|.|......:.|.|...:||:|::: :..|.:|   |:     :.|..:.:...
 Frog    62 TECFKKYGKMWGTYDGRQPVLAIMDPAIIKTILVKECYTNFTNRRNFGL-----NGPFESAITIA 121

  Fly   123 EGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIG 187
            |.::||.:|..|:.||||.|:|.||..:.:..|.:::.:...: ...:.....|::..::.|||.
 Frog   122 EDEQWKRIRNVLSPTFTSGKLKEMFQIMKDYSDILVKNIQGYV-EKDEPCATKDVIGAYSMDVIT 185

  Fly   188 ICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGM--PKLAVKLGFQFLLPSVQ---- 246
            ..:|.:..:||..|...||          .|  :..||..|:  |.|.:.:.|.||.|.::
 Frog   186 STSFSVNIDSLNKPSDPFV----------IH--MKKLLKTGLLSPLLILVVIFPFLRPILEGLNL 238

  Fly   247 --------KFYMKIVQDTIDYRMKRK----VTRNDFMDTLIDMKQQ--YDKGDKENGLAFNEVAA 297
                    :|:|..|   ..:|.|||    ..|.|.:..::|.:..  .|..:|...|...|:.|
 Frog   239 NFVPKDFTEFFMNAV---TSFREKRKKGDHSGRVDLLQLMMDSRTTGGNDLSNKHKALTDAEIMA 300

  Fly   298 QAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVIN 362
            |:.:|.:||:|..||.:.:..|.||.:.|||.:|..||||.|.. .....||.:..:.|::.||.
 Frog   301 QSVIFIVAGYETTSTALSYLFYNLATHPDVQQRLHEEIDSFLPD-KASPTYDILMQMEYLDMVIQ 364

  Fly   363 ESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQV 427
            |:||..|....|.|::.:..:.:...  |..|...|:....:..|||::||||:|.||||.:|..
 Frog   365 ETLRLFPPAGRLERVSKQNVEINGVS--IPKGIVTLIPAYVLQRDPEYWPEPEEFRPERFSKENR 427

  Fly   428 KKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYT 481
            .......|||||.||||||||||..:.:.:.:..|:.||......:|.:||:::
 Frog   428 ATHTPFTFLPFGDGPRNCIGLRFALLSMKVAIVTLLQNFSVRPCAETLIPMEFS 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	139/484 (29%)
cyp3a4.2	NP_001015786.1	p450	39..496	CDD:365848	139/484 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	239	1.000	Domainoid score	I2234
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3174
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060