Protein Alignment Cyp6a19 and Cyp3a41a

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 510
• Identity: 151/510 - (29%)
• Similarity: 260/510 - (50%)
• Gaps: 64/510 - (12%)

  Fly     3 ILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILK---RTYLKFR 64
            :||.:   :|.|:..:..:.:..:|::|||...|...||.....::     |:.|   ..|.|:.
Mouse    13 VLLAI---ILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYK-----GLWKFDMECYEKYG 69

  Fly    65 KQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDR------GVYHNEKDDPLTNNLATI 122
            | |.|.|.|    .|...||||.:.:|.||::: |..|.:|      |:        ::..::..
Mouse    70 K-TWGLFDG----QMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGI--------MSKAISIS 121

  Fly   123 EGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIG 187
            :.::||..|..|:.||||.|:|.||..:...||.:::.:.:: :...:.:.:.|::..::.|||.
Mouse   122 KDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQE-AEKGKPVTMKDVLGAYSIDVIT 185

  Fly   188 ICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLP--------- 243
            ..:||:..:||.:|:..||:.....||..    ..|.|:|.:      :.|.||.|
Mouse   186 STSFGVNVDSLNNPEDPFVEKAKGILRVD----FFDPLVFSV------VLFPFLTPVYEMLNICM 240

  Fly   244 ----SVQ---KFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFV 301
                |::   ||..::.:..:|.:.|.:|   ||:..:::........|....|:..|:.||:.|
Mouse   241 FPKDSIEFFKKFVNRMKESRLDSKQKHRV---DFLQLMMNAHNNSKDKDSHKALSDMEITAQSIV 302

  Fly   302 FFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLR 366
            |..||:|..|:|:.||||.||.:.|:|.||:.|||..|.. .....||::.::.|::.|:||:||
Mouse   303 FIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPN-KAPPTYDTVMEMEYLDMVLNETLR 366

  Fly   367 KHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRP 431
            .:|:...|.|...|..:.:.  .:|..|:.|::.:..:||||:.:||||:|.||||.:|......
Mouse   367 LYPIGNRLERFCKKDVELNG--VYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSID 429

  Fly   432 TCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLL 486
            ...::|||.|||||||:||..|.:.:.|..::.||.|:...:|.:|:|.:...||
Mouse   430 PYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	144/481 (30%)
Cyp3a41a	NP_059092.2	p450	39..494	CDD:278495	144/481 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720