Protein Alignment Cyp6a19 and Cyp4a1

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_787031.1
• Gene: Cyp4a1 / 50549
• RGDID: 68945
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 123/466 - (26%)
• Similarity: 201/466 - (43%)
• Gaps: 78/466 - (16%)

  Fly    71 FAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTN------------NLATIE 123
            |..::..:..|:::.|.|::|.:|.|               .||..|            .|..:.
  Rat    85 FPRWFWGSKAYLIVYDPDYMKVILGR---------------SDPKANGVYRLLAPWIGYGLLLLN 134

  Fly   124 GQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVD--EKISSSSQTLEVTDIVSRFTSDVI 186
            ||.|...|:.||..|....:|..   |.|:.|.:..::|  |:::....::|:...:|..|.|.:
  Rat   135 GQPWFQHRRMLTPAFHYDILKPY---VKNMADSIRLMLDKWEQLAGQDSSIEIFQHISLMTLDTV 196

  Fly   187 GICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLL-----IFGMP------KLAVKLGFQF 240
            ..|||....:...|...:........|.:..|..:.::.     |:...      ..|.:|....
  Rat   197 MKCAFSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDTIYNFSSNGHLFNRACQLAHDH 261

  Fly   241 LLPSVQKFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENG--LAFNEVAAQAFVFF 303
             ...|.|.....:|:..:....:|..|.||:|.|:..:.       |||  |:..::.|:...|.
  Rat   262 -TDGVIKLRKDQLQNAGELEKVKKKRRLDFLDILLLARM-------ENGDSLSDKDLRAEVDTFM 318

  Fly   304 LAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKH 368
            ..|.:..::.:.:..|.||.:.:.|.:.|.|:.|||.. ...:.:|.:..:.|....|.|:||.:
  Rat   319 FEGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLGD-GSSITWDHLDQIPYTTMCIKEALRLY 382

  Fly   369 P----VVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKK 429
            |    :|..|:...|.|...|.||     |..|.:|..|:||:|:.:|.||.|.|.||..:  ..
  Rat   383 PPVPGIVRELSTSVTFPDGRSLPK-----GIQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD--SP 440

  Fly   430 RPTCAFLPFGAGPRNCIGLRF--GRMQVIIGLALLIHNFRFELHP---KTPVPMKYTINNLLLGS 489
            |.:.:||||..|.|||||.:|  ..|:||:.|.||    ||||.|   |.|:|:.    .|:|.|
  Rat   441 RHSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLL----RFELLPDPTKVPIPLP----RLVLKS 497

  Fly   490 EGGIHLNITKV 500
            :.||:|.:.|:
  Rat   498 KNGIYLYLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	120/458 (26%)
Cyp4a1	NP_787031.1	CYP4B-like	71..504	CDD:410771	121/460 (26%)