Protein Alignment Cyp6a19 and Cyp4f40

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001102830.1
• Gene: Cyp4f40 / 503122
• RGDID: 1559596
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 143/547 - (26%)
• Similarity: 234/547 - (42%)
• Gaps: 102/547 - (18%)

  Fly     3 ILLGLVVGVLTLVAWWVLQNYTYWKR----RGIPHDPPNIPL-GNTG-------------ELWRT 49
            :||.| |||...:...:.|.||.:.:    .|.|..|..... |:.|             ||..|
  Rat    20 LLLSL-VGVSWFLTRCLTQIYTLYAKCQRLCGFPQPPKRSWFWGHLGMSPPTEEGMKQMTELVAT 83

  Fly    50 MPLAGILKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDP 114
            .| .|.:  |:|       ||.       :..|.:...|.:::||..........|::::.....
  Rat    84 YP-QGFM--TWL-------GPI-------VPLITLCHPDIIRSVLSASAAVAPKDGIFYSFLKPW 131

  Fly   115 LTNNLATIEGQKWKNLRQKLTHTFTSAKMK---SMFSTVLNV-GDEMIRVVDEKISSSSQTLEVT 175
            |.:.|......||...|..||..|....:|   .:|:...|: ..:.:|:.    |..|..|::.
  Rat   132 LGDGLLVSASDKWSRHRSMLTPAFHFNILKPYVKIFNDSTNIMHAKWLRLA----SGGSAHLDMF 192

  Fly   176 DIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQ--MGYSALRERRHGWL---VDLLIFGMPKLAVK 235
            :.:|..|.|.:..|.|....|....| :|::.  :..|||..:|:..|   :|||
  Rat   193 ENISLMTLDTLQKCVFSFNSNCQEKP-SEYIAAILELSALVVKRNEQLLLHMDLL---------- 246

  Fly   236 LGFQFLLPSVQKFY----------MKIVQ------------DTIDYRMKRKVTRNDFMDTLIDMK 278
               ..|.|..::||          ..::|            |.|..:.|.|..  ||:|.|:..|
  Rat   247 ---YRLTPDGRRFYKACHLVHDFTYAVIQERRRTLPKHGGDDVIKAKAKSKTL--DFIDVLLLSK 306

  Fly   279 QQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVL-ERY 342
               |:..||  |:..::.|:|..|...|.:..::.:.:.||.||.:.:.|::.|.|:..:| :|.
  Rat   307 ---DEDGKE--LSDEDIRAEADTFMFEGHDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRD 366

  Fly   343 NGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHD 407
            :.::|:|.:..|.::...|.||||.||.|..::|..|:.....:.: .|..|...:::....||:
  Rat   367 SEEIEWDDLAQLPFLTMCIKESLRLHPPVTMVSRCCTQDISLPDGR-VIPKGIICIINIFATHHN 430

  Fly   408 PEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRF--GRMQVIIGLALLIHNFRFEL 470
            |..:.:||.:.|.|||.|.::.|...||:||.||||||||..|  ..|:|.:.|.||    ||.:
  Rat   431 PTVWQDPEVYDPFRFDPENIQARSPLAFIPFSAGPRNCIGQTFAMNEMKVAVALTLL----RFRV 491

  Fly   471 HPKTPVPMKYTINNLLLGSEGGIHLNI 497
            .|....|.:..  .|:|.:|.|:.|.:
  Rat   492 LPDDKEPRRKP--ELILRAEDGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	121/460 (26%)
Cyp4f40	NP_001102830.1	CYP4F	74..515	CDD:410772	128/489 (26%)