Protein Alignment Cyp6a19 and LOC4577431

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_001237417.1
• Gene: LOC4577431 / 4577431
• VectorBaseID: AGAMI1_011574
• Length: 462
• Species: Anopheles gambiae
• Alignment Length: 523
• Identity: 115/523 - (21%)
• Similarity: 201/523 - (38%)
• Gaps: 98/523 - (18%)

  Fly    12 LTLVAWWVLQNYT------------------YWKRRGIPHDPPNIPL-GNTGELWRTMPLAGILK 57
            :.:|.:|:....|                  .|..|..|.......| |:.|...||.......:
Mosquito     1 MPIVEFWIALGTTVLLTGAFGLCLILDKRRSLWVDRRFPSTGRTCVLYGDYGAAGRTEHRIYTTQ 65

  Fly    58 RTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATI 122
            |.|.:| |....|..|..:|....::.||...::.:|..:|.|                |..::|
Mosquito    66 RLYREF-KSKKWPIGGALMYLTPCVIPTDPHLIEFLLNEEFGK----------------NKKSSI 113

  Fly   123 EG-----QKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFT 182
            .|     ::|.:...:  |          :::::||..|....|.|.:.:|.|.::|..|...:.
Mosquito   114 AGSSIFRKRWSSFEDE--H----------YNSLVNVATEESEKVVEMLCTSKQPVDVKVIAELYA 166

  Fly   183 SDVIGICAFGLKC--NSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSV 245
            ..:|..|.||.:|  .|...|..|       .|..:..|.:.|:.....|........:.||...
Mosquito   167 VRMIARCVFGKRCTEESHTFPITE-------KLASQPGGIVWDVFSTAFPSTTFTATLRKLLDHF 224

  Fly   246 QKFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAF-----VFFLA 305
            || :..::.:.:...:..:....:|:..|   |:...:......:||.:..|...     |||:|
Mosquito   225 QK-HPALLDELVSSFLTERTADVNFLQHL---KRTEQRAKANERIAFGDTRALMLELVQNVFFVA 285

  Fly   306 GFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPV 370
                 |.|:...|:|:..|.|:|..|.    ..|:|.| ....|:      :|.||:|:|||:|.
Mosquito   286 -----SGTIIACLFEMGHNGDIQKGLH----ETLQRSN-PFAVDT------LENVISETLRKYPP 334

  Fly   371 VAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPER----FDEEQVKKRP 431
            |..::.:.....:..:.:..:...|.|:|....:.||.|.||:||:|.|:|    ..|:.|..|
Mosquito   335 VGEISFVTVANNRLPSGELVVPKNTRVVVPIYALQHDAEHYPDPERFNPKRSIFSSSEQSVLYR- 398

  Fly   432 TCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLN 496
                 |.|..|.. ||.....:.|.:.|:.::......|.|::|..:|.:.|..:....|.:.|.
Mosquito   399 -----PLGVQPLP-IGSSLALLMVRVALSNILGRCTVRLTPESPATLKISPNQAMPYPTGRVELL 457

  Fly   497 ITK 499
            |::
Mosquito   458 ISR 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	98/442 (22%)
LOC4577431	XP_001237417.1	cytochrome_P450	74..454	CDD:477761	98/441 (22%)