Protein Alignment Cyp6a19 and Cyp4c3

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 140/560 - (25%)
• Similarity: 230/560 - (41%)
• Gaps: 126/560 - (22%)

  Fly     2 AILLGLVVGVLTLVAWWVLQNYTYWKRRG--------IPHDPPNIP-LGNTGE------------ 45
            :||:.|||               |.|||.        || .|..:| |||..|
  Fly    36 SILIFLVV---------------YNKRRSRLVKYIEKIP-GPAAMPFLGNAIEMNVDHDELFNRV 84

  Fly    46 -----LWRTMPLAGILKRTY-------LKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDF 98
                 ||.|.  .|| .|.:       |.|..:|..|.    |.:.|::
  Fly    85 IGMQKLWGTR--IGI-NRVWQGTAPRVLLFEPETVEPI----LNSQKFV---------------- 126

  Fly    99 DKFHDRGVYHNEKDDP-LTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVD 162
            :|.||....|     | |...|.|...:||.:.|:.||..| ..|:...|..|.|   |...|:.
  Fly   127 NKSHDYDYLH-----PWLGEGLLTSTDRKWHSRRKILTPAF-HFKILDDFIDVFN---EQSAVLA 182

  Fly   163 EK--ISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGY---SALRERRHG-WL 221
            .|  :...|:...:...|:..|.|::...|.|.:..:..:.::|:|:..|   |.::.|:.. ||
  Fly   183 RKLAVEVGSEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWL 247

  Fly   222 VDLLIFGMPKLAVKL---------GFQFLLPSVQKFYMKIVQ-----------DTIDYRMKRKVT 266
            ....||.: ....||         ||..::...:|..:.|:|           |..|...|:|
  Fly   248 QSDFIFSL-TAEYKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKK-- 309

  Fly   267 RNDFMDTLIDMKQQYDKGDKENGLAFNE-VAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDK 330
            |..|:|.|||       ..||..:..|| :..:...|...|.:..|..:.:||:.|.|:.:.|::
  Fly   310 RLAFLDLLID-------ASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQER 367

  Fly   331 LRAEIDSVL-ERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAG 394
            :..|:||:. :.........::.|:.|:|..|.:|||..|.|..:||:..:.......  .:.||
  Fly   368 VVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGK--IVPAG 430

  Fly   395 TGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGL 459
            |..::.|..:|.:|..:|:||:|.|:.|..|....|...|::||.||||||||.:|..::....:
  Fly   431 TQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVI 495

  Fly   460 ALLIHNFRFE-LHPKTPVPMKYTINNLLLGSEGGIHLNIT 498
            :.::..::.| :..:..:.:   :..|:|..:.|:.:.||
  Fly   496 STVLRKYKIEAVDRREDLTL---LGELILRPKDGLRVKIT 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	113/456 (25%)
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	118/477 (25%)