Protein Alignment Cyp6a19 and cyp-25A3

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 151/521 - (28%)
• Similarity: 229/521 - (43%)
• Gaps: 78/521 - (14%)

  Fly     3 ILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRT-------- 59
            ||..::|.:::.:.:.:|.....::.||      .|.|......|....|..|::|.
 Worm     5 ILTSILVSLVSFIIYVILARKERFRLRG------KIGLSGPEPHWLMGNLKQIIERKAKLGYDDS 63

  Fly    60 ---YLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRG----VYHNEKDDPLTN 117
               |.|..||....| |.|......|.||:.:.:|.|.|::|..|.||.    :..|:..:.|..
 Worm    64 YDWYNKLHKQFGETF-GIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLKESLLQ 127

  Fly   118 NLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFT 182
            |  |.| ..||:.|..:...|::.|||:|..|:.:..|..:.::.|| :||.|..::.|.....|
 Worm   128 N--TYE-SGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEK-ASSGQKWDIYDDFQGLT 188

  Fly   183 SDVIGICAFGLKCNSLRDPKAEFVQMGYSALR------ERRHGWLVDLLIFGMPKLAVKLGFQFL 241
            .||||.|||.:..|..||....|    |...|      :.||..::. ..|..|:|:......:.
 Worm   189 LDVIGKCAFAIDSNCQRDRNDVF----YVNARKFITNIDIRHSKIIS-TSFLFPELSKLWKVLYR 248

  Fly   242 LPSVQKFYMKIVQDTID-YRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLA 305
            ...:.|..:.:|:...| |..:|....:|.:|.|..:..:.|  ||...:...||....|.|.||
 Worm   249 FTDLAKAEIPLVEGLADVYERRRGGEGSDSVDLLKLLLNRED--DKSKPMTKQEVIENCFAFLLA 311

  Fly   306 GFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPV 370
            |:|..||.|.:..|.|:...:||.||..||....|  ||.|.|||:.::.|::.|..|:||.:|.
 Worm   312 GYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKE--NGGLTYDSIHNMKYLDYVYKETLRCYPP 374

  Fly   371 VAHLARIATKPYQHSNPK---------YFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQ 426
            |.|.          ||.:         .|...|..|:.....:|.:||.:..||:|.|||| |..
 Worm   375 VIHF----------SNRRCLKDITIRGQFYPKGAIVVCLPHTVHRNPENWDSPEEFHPERF-ENW 428

  Fly   427 VKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNF---RFE-------------LHPKTP 475
            .:|..:..::|||.|||.|:|:||..|:....:|.|:..|   :||             :.||.|
 Worm   429 EEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELKQFEGEADLIPDCNGVIMRPKDP 493

  Fly   476 V 476
            |
 Worm   494 V 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	135/446 (30%)
cyp-25A3	NP_001040850.1	CYP3A-like	73..495	CDD:410678	136/447 (30%)