Protein Alignment Cyp6a19 and Cyp4a30b

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_006503285.1
• Gene: Cyp4a30b / 435802
• MGIID: 3717145
• Length: 510
• Species: Mus musculus
• Alignment Length: 551
• Identity: 139/551 - (25%)
• Similarity: 231/551 - (41%)
• Gaps: 119/551 - (21%)

  Fly     4 LLGLVVGVLTLVAWWVLQNYTYWKRRGI----PHDPPNIPLGNT---GELWRTMPLAGILKRTYL 61
            ||||::.:|....:::   :..|..:.:    |..||....|||   .:|.:.:........||:
Mouse    24 LLGLLLLLLKSAQYYL---HRQWLIKSLQQFPPAPPPQWLFGNTLKDQDLQQILLCVEKFPSTYV 85

  Fly    62 KFRKQTDGPFAGFYLYA-MKYIVITDVDFVKTVL-------IRDFDKFHDRGVYHNEKDDPLTNN 118
            :            :|:. ...:||.|.|::|.:|       :|.:..|.....|          .
Mouse    86 R------------WLWGNHARVVIYDPDYMKVILGRSDPKVVRSYSFFAPWIGY----------G 128

  Fly   119 LATIEGQKWKNLRQKLTHTFTSAKMKS----MFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVS 179
            |..:.|:||...|:.||..|....:|.    |..:|..:.|:..::||:..     .||:...:|
Mouse   129 LLLLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDC-----PLEIYQDIS 188

  Fly   180 RFTSDVIGICAF----GLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQ- 239
            ..|.:.:..|||    .::....|:.|:..     .|:.:..|      ||:    |.|:.||.
Mouse   189 LMTMETMMKCAFSYQGSVQLEDCRNSKSYI-----KAVEDLTH------LIY----LRVRNGFHQ 238

  Fly   240 -----FLLPSVQKFYMKI-----------------VQDTIDYRMKRKVTRNDFMDTLIDMKQQYD 282
                 .|..:.:.||...                 :|:..:....||..|.||:|.|:     :.
Mouse   239 NNTIYSLSSNGRSFYHACQIAHKHTERVIRMRKAQLQNEAELEKFRKKKRLDFLDILL-----FA 298

  Fly   283 KGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNG-KL 346
            :.:....|:..:|.|:...|...|....::.:.:..|.||.:.:.|.:.|.|:.|:|.  || .:
Mouse   299 QTEDGKSLSDEDVRAEMDTFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILG--NGTSV 361

  Fly   347 EYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQH----SNPKYFIEAGTGVLVSTLGIHHD 407
            ..:.:..:.|....|.|:||.:|.:...:|..:.|...    |.||.|:     |.:|..|:||:
Mouse   362 TLNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVTFPDGCSLPKGFL-----VTLSFYGLHHN 421

  Fly   408 PEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRF--GRMQVIIGLALLIHNFRFEL 470
            |...|..|.|.|.||  .....|.|.|||||.||.|||||.:|  ..::|.:.|.||    ||||
Mouse   422 PRLRPNAEVFDPSRF--APGAPRQTHAFLPFSAGTRNCIGKQFTMNELKVAVALTLL----RFEL 480

  Fly   471 HP-KTPVPMKYTINNLLLGSEGGIHLNITKV 500
            .| .|.||:  .::.::|.|:.||:|:..|:
Mouse   481 LPDPTRVPI--LVSKIVLKSKNGIYLHTKKL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	121/473 (26%)
Cyp4a30b	XP_006503285.1	CYP4B-like	70..505	CDD:410771	125/496 (25%)