Protein Alignment Cyp6a19 and Cyp4d8

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 544
• Identity: 131/544 - (24%)
• Similarity: 237/544 - (43%)
• Gaps: 90/544 - (16%)

  Fly     3 ILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDP-PNIPLGNTGELWRTMPLAGILK-------RT 59
            :||.|:| ||...|.|::......:||.:.:.| |..|           ||.|.::       :|
  Fly     1 MLLFLLV-VLLFGAGWIIHLGQADRRRKVANLPGPICP-----------PLIGAMQLMLRLNPKT 53

  Fly    60 YLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEK---DDP------- 114
            ::|..::          |.:|:..:..|.....:||...|...:..:..:::   ..|
  Fly    54 FIKVGRE----------YVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQ 108

  Fly   115 -LTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKIS--SSSQTLEVTD 176
             |.|.|...:|:.|...|:.:|.||..    |:....:.|.|:...:..::::  ::..|.:|..
  Fly   109 WLGNGLLLSDGKVWHQRRKIITPTFHF----SILEQFVEVFDQQSNICVQRLAQKANGNTFDVYR 169

  Fly   177 IVSRFTSDVIGICAFGLKCNSLRD---PKAEFVQMGYSALRER-RHGWLVDLLIFGMPKLAVKLG 237
            .:.....|:|...|.|.|..:..:   |.||.|....:.|..| ...:|...|:|.:....:|..
  Fly   170 SICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWR 234

  Fly   238 FQFLLPSVQKFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKE--------------- 287
            ...|:.::|:|.:|:::       ||:....|....|:|...: |.|.|.
  Fly   235 QTQLIRTMQEFTIKVIE-------KRRQALEDQQSKLMDTADE-DVGSKRRMALLDVLLMSTVDG 291

  Fly   288 NGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGK-LEYDSM 351
            ..|..:|:..:...|...|.:..::.:.|.|:||:.:.:||.|:..||..||.....: :....:
  Fly   292 RPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDL 356

  Fly   352 QDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKY---FIEAGTGVLVSTLGIHHDPEFYPE 413
            .:|.|||.||.||||.:|.|..:.|.....:::::..:   .|.||:.:::...|:|..||.:|.
  Fly   357 GELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPN 421

  Fly   414 PEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPM 478
            |::|||||  .|...:......:||.||||||||.:|.::::.:.||.::..:..       :||
  Fly   422 PDEFIPER--HENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYEL-------LPM 477

  Fly   479 KYTIN---NLLLGSEGGIHLNITK 499
            ...:.   |::|.||.|..|.:.|
  Fly   478 GQRVECIVNIVLRSETGFQLGMRK 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	111/465 (24%)
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	109/451 (24%)