DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp6a19 and Cyp309a2

DIOPT Version :9

Sequence 1:NP_611001.2 Gene:Cyp6a19 / 36662 FlyBaseID:FBgn0033979 Length:503 Species:Drosophila melanogaster
Sequence 2:NP_608689.2 Gene:Cyp309a2 / 33439 FlyBaseID:FBgn0041337 Length:538 Species:Drosophila melanogaster


Alignment Length:492 Identity:124/492 - (25%)
Similarity:224/492 - (45%) Gaps:37/492 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 ILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGN-TGELWRTMPLAGILKRTYLKFRKQ 66
            |||.|:|..:.|...|   ::.||::||:....|...||. .|.|.|...|...:::.|.|::.:
  Fly    41 ILLHLLVLPIYLYLTW---HHKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVFDVQKIYDKYKGK 102

  Fly    67 TDGPFAGFYLYAMKYIVITDVDFVKTVLIRDF----DKFHDRGVYHNEKDDPLTNNLATIEGQKW 127
            ...  .|.::.....|::.|.:....||:.:|    |......:.|.:.|.....|.....||.|
  Fly   103 HRA--VGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDKYARLNPFWASGQSW 165

  Fly   128 KNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFG 192
            :.||.......:.::::..::.....|..:...:.::::..:..||..|:..|:|:.|:....:|
  Fly   166 RRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVMADFIWG 230

  Fly   193 LKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFG---MPKLAVKLGFQFLLPSVQKFYMKIVQ 254
            :...:|..|..:..::...|.:...:.:.:..|...   .|...:.|.|:|......:|:..:.:
  Fly   231 IDAGTLTRPMEQPNKVQEMASKWTSYAFYMLTLFMATIVAPCSRLLLRFRFYPKETDEFFSNLTK 295

  Fly   255 DTIDYRMKR-KVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTL 318
            ::|:.|:|. ..||.|::..|:.::.|       .....:::...|....|.|::...|.:...|
  Fly   296 ESIELRLKAGDSTRTDYLSHLLQLRDQ-------KQATHDDLVGHALTVMLDGYDTSGTALLHAL 353

  Fly   319 YELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKP-- 381
            |.||.|..||.|||.||.|.:.. ...|:::.:..|.|:|:||.||||...::....::.|.|  
  Fly   354 YYLAENPAVQQKLRVEILSCMAS-EKSLDFEKLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTV 417

  Fly   382 YQHSNPKYF-IEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFD----EEQVKKRPTCAFLPFGAG 441
            .:.|..|.. :|.|..:::.....|||.:::||||.|.|||||    :|.::|.   .||||..|
  Fly   418 IRLSESKSLDVEVGMTIMIPNYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKG---IFLPFSDG 479

  Fly   442 PRNCIGLRFGRMQVIIGLALLIHNF-----RFELHPK 473
            ||.|:|:....:.:...|..::.||     |..|.||
  Fly   480 PRICMGVPLAMLTLKSALVHILSNFQVVRGRDRLIPK 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp6a19NP_611001.2 p450 32..495 CDD:278495 113/463 (24%)
Cyp309a2NP_608689.2 p450 70..526 CDD:299894 113/460 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45460998
Domainoid 1 1.000 88 1.000 Domainoid score I2119
eggNOG 1 0.900 - - E2759_KOG0158
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 161 1.000 Inparanoid score I1621
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24292
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
76.900

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