Protein Alignment Cyp6a19 and Cyp6t1

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 511
• Identity: 150/511 - (29%)
• Similarity: 262/511 - (51%)
• Gaps: 21/511 - (4%)

  Fly     3 ILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYLKFRKQT 67
            :|.|..:.|:|:|..|.:.::.:|:|.|:|..|....:||...|.|.....|...|...:.::..
  Fly    23 VLRGGCLLVVTIVWLWQILHFWHWRRLGVPFVPAAPFVGNVWNLLRGACCFGDQFRELYESKEAA 87

  Fly    68 DGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPL-----TNNLATIEGQKW 127
            ...|.|..:.....:::.|...:|.:::.||.:|..|    .|..||.     :.||...:.:.|
  Fly    88 GRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQFSSR----FETTDPTCDTMGSQNLFFSKYETW 148

  Fly   128 KNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISS-SSQTLEVTDIVSRFTSDVIGICAF 191
            :...:.....|.:.|:::|:..:.|:|.::...:::|:|. .|..|||..:.:.||:|:|...||
  Fly   149 RETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCALFTTDIIASLAF 213

  Fly   192 GLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQDT 256
            |::.:||::|:|||.:|.......|....|....:|..|:|:.::|........::|..|.:...
  Fly   214 GIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHLFTMFFFPRLSHRVGTHLYSEEYERFMRKSMDYV 278

  Fly   257 IDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYEL 321
            :..|.:....|:|.:|..:.:|:........:...|  .||||....||||:..|:|:.|.||||
  Fly   279 LSQRAESGENRHDLIDIFLQLKRTEPAESIIHRPDF--FAAQAAFLLLAGFDTSSSTITFALYEL 341

  Fly   322 ACNQDVQDKLRAEIDSVLE-RYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIAT------ 379
            |.|..:||:||.|:.:.|: ..:.:|..|::..|.|:.:|::|.||.:|..|.|.|...
  Fly   342 AKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYD 406

  Fly   380 -KPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPR 443
             .|:...:| :.:.|||.|.:|.||||.|.:::|.||.|.||||..||.::.....:||||||||
  Fly   407 LSPWNGGSP-FKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPFGAGPR 470

  Fly   444 NCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLNITK 499
            .|||...|::::.:||..::::||.|:..:|...|::.....:|.:..|.:|...|
  Fly   471 GCIGTLLGQLEIKVGLLHILNHFRVEVCERTLPEMRFDPKAFVLTAHNGTYLRFVK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	139/476 (29%)
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	129/430 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461070
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900