Protein Alignment Cyp6a19 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 446
• Identity: 121/446 - (27%)
• Similarity: 203/446 - (45%)
• Gaps: 56/446 - (12%)

  Fly    82 IVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTN---NLATIEGQKWKNLRQKLTHTFTSAKM 143
            :::.|.|:||.||.|...|  ..|:|.......::.   .|..:.|:||....:.||..|....:
  Rat    94 VLLYDPDYVKVVLGRSDPK--ASGIYQFLAPWIVSGTGYGLLLLNGKKWFQHWRMLTPAFHYGIL 156

  Fly   144 KSMFSTVLNVGDEMIRVVD--EKISSSSQTLEVTDIVSRFTSDVIGICAFG------LKCNSLRD 200
            |..   |..:.|.:..::|  ||:......||:...||..|.|.:..|||.      |..||...
  Rat   157 KPY---VKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSY 218

  Fly   201 PKA--EFVQMGYSALRERRHGWLVDLLIFGM------PKLAVKLGFQFLLPSVQKFYMKIVQDTI 257
            .||  :...:.:..:|...:|   :.:|:.|      .:.|.::..:. ...|.|.....:|:..
  Rat   219 TKAVEDLNNLTFFRVRSAFYG---NSIIYNMSSDGRLSRRACQIAHEH-TDGVIKMRKAQLQNEE 279

  Fly   258 DYRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELA 322
            :.:..||....||:|.|:..|.:..|     .|:..::.|:...|...|.:..::.:.:..|.||
  Rat   280 ELQKARKKRHLDFLDILLFAKMEDGK-----SLSDEDLRAEVDTFMFEGHDTTASGISWVFYALA 339

  Fly   323 CNQDVQDKLRAEIDSVLERYNG-KLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQ--- 383
            .:.:.|::.|.|:.|:|.  :| .:.:|.:..:.|....|.|:||.:|.|..::|..:.|..
  Rat   340 THPEHQERCREEVQSILG--DGTSVTWDHLDQISYTTMCIKEALRLYPPVPSVSRELSSPVTFPD 402

  Fly   384 -HSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIG 447
             .|.||     |....:...|:||:|.::|.|:.|.|.||..:  ..|.:.|:|||..|.|||||
  Rat   403 GRSIPK-----GITTTILIYGLHHNPSYWPNPKVFDPSRFSPD--SPRHSHAYLPFSGGARNCIG 460

  Fly   448 LRFGRMQVIIGLALLIHNFRFELHP---KTPVPMKYTINNLLLGSEGGIHLNITKV 500
            .:|...::.:.:||.:  .||||.|   :.||||.    .|:|.|:.||||.:.|:
  Rat   461 KQFAMNELKVAVALTL--LRFELLPDPTRIPVPMA----RLVLKSKNGIHLRLKKL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	117/438 (27%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	119/440 (27%)