Protein Alignment Cyp6a19 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001028858.2
• Gene: Cyp4f18 / 290623
• RGDID: 1305261
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 141/547 - (25%)
• Similarity: 231/547 - (42%)
• Gaps: 103/547 - (18%)

  Fly     4 LLGLVVGVLTLVAWWVLQNYTYWKR----RGIPHDPP-NIPLGNTGELWRTMPLAGILKRTYLKF 63
            ||.|:||...|:|:.:.|.|..::.    |..|..|. |...|:.|.:..:.  .|:|   |::.
  Rat    20 LLLLLVGASCLLAYILPQVYAVFENSRRLRRFPQPPTRNWLFGHLGLIQSSE--EGLL---YIQS 79

  Fly    64 RKQT--------DGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLA 120
            ..:|        .||:       ...|.|....|:|.|::..........|::......|.:.|.
  Rat    80 LSRTFRDVCCWWVGPW-------HPVIRIFHPAFIKPVILAPASVAPKDRVFYRFLKPWLGDGLL 137

  Fly   121 TIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISS-SSQTLEVTDIVSRFTSD 184
            ...|.||...|..||..|....:|. :..:.|....::....::::| .|..|::.:.:|..|.|
  Rat   138 LSTGDKWSRHRHMLTPAFHFNILKP-YVKIFNDSTNIMHAKWQRLASQGSARLDMFEHISLMTLD 201

  Fly   185 VIGICAFGLKCNSLRDPKAEFVQ--MGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQK 247
            .:..|.|....|....| :|::.  :..|||..|||                    |.||..|..
  Rat   202 SLQKCVFSFDSNCQEKP-SEYITAILELSALVARRH--------------------QSLLLYVDL 245

  Fly   248 FY------------MKIVQDTID------------------YRMKRKVTRNDFMDTLIDMKQQYD 282
            ||            .::|.|..|                  .:.|.|....||:|.|:..|.::.
  Rat   246 FYHLTRDGMRFRKACRLVHDFTDAVIRERRRTLPDQGGDDALKAKAKAKTLDFIDVLLLSKDEHG 310

  Fly   283 KGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVL-ERYNGKL 346
            :     .|:..::.|:|..|...|.:..::.:.:.||.||.:.:.|::.|.|:..:| :|...::
  Rat   311 E-----ALSDEDIRAEADTFMFGGHDTTASGLSWILYNLAKHPEYQERCRQEVRELLRDREPEEI 370

  Fly   347 EYDSMQDLFYMEKVINESLRKHPVVAHLARIATK----PYQHSNPKYFIEAGTGVL--VSTLGIH 405
            |:|.:..|.::...|.||||.||....::|..|:    |.....||       ||:  :|..|.|
  Rat   371 EWDDLAQLPFLTMCIKESLRLHPPATAISRCCTQDIMLPDGRVIPK-------GVICRISIFGTH 428

  Fly   406 HDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFEL 470
            |:|..:|:||.:.|.|||.:..:.|...||:||.||||||||..|...::.:.|||.:  .||.:
  Rat   429 HNPAVWPDPEVYNPFRFDADNGEGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTL--LRFRV 491

  Fly   471 HPKTPVPMKYTINNLLLGSEGGIHLNI 497
            .|....|.:..  .|:|.:|||:.|.:
  Rat   492 LPDDKEPRRKP--ELILRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	122/474 (26%)
Cyp4f18	NP_001028858.2	CYP4F	74..515	CDD:410772	124/488 (25%)