Protein Alignment Cyp6a19 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 459
• Identity: 112/459 - (24%)
• Similarity: 198/459 - (43%)
• Gaps: 51/459 - (11%)

  Fly    48 RTMPLAG---ILKRTYLKFRKQ----TDG----PFAGFYLYAMKYIVITDVDFVKTVLIRDFDKF 101
            |..||.|   .:|....:|.:|    |:.    |....::..:..:.:...:.|:.:|..  .|.
  Rat    55 RAYPLVGHALFMKPNNTEFFQQIIQYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTS--SKQ 117

  Fly   102 HDRGVYHNEKDDPLTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKIS 166
            .|:...:......|...|.|..|.||:..|:.||.:|..    ::....|:|.:|...::..|:.
  Rat   118 IDKSFMYKFLQPWLGLGLLTSTGSKWRARRKMLTPSFHF----TILEDFLDVMNEQANILVNKLE 178

  Fly   167 S--SSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGY----SALRERRHGWLVDLL 225
            .  :.:.......::....|:|...|.|....:..:..:|:|:..|    ...|..:..|    .
  Rat   179 KHVNQEAFNCFFPITLCALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPW----F 239

  Fly   226 IFGMPKLAVKLGFQFL--LPSVQKFYMKIVQDTIDYR-------------MKRKVTRNDFMDTLI 275
            .|.:..|..|.|....  |.|:..|...::.:.::.|             :..|..|..|:|.|:
  Rat   240 WFDLWYLMFKEGRDHKKGLKSLHTFTNNVIAERVNARKAEQDCIGAGRGPLPSKTKRKAFLDLLL 304

  Fly   276 DMKQQYDKGDKE-NGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVL 339
            .:.      |:| |.|:..::..:...|...|.:..:..:.::||.|..|.:||.|:..|:|.|.
  Rat   305 SVT------DEEGNKLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVF 363

  Fly   340 ERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGI 404
            .|.:..:..:.::.|.|::.||.|:||..|.|...||..::..:.:.  |.|..||..::....:
  Rat   364 GRSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAG--YKISKGTEAVIIPYAL 426

  Fly   405 HHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFE 469
            |.||.::|:||:|.||||..|..:.|...|::||.||||||||.:|..|:....||.::..|..|
  Rat   427 HRDPRYFPDPEEFQPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREFWIE 491

  Fly   470 LHPK 473
            .:.|
  Rat   492 SNQK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	105/433 (24%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	106/438 (24%)