Protein Alignment Cyp6a19 and Cyp3a23-3a1

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 522
• Identity: 153/522 - (29%)
• Similarity: 253/522 - (48%)
• Gaps: 85/522 - (16%)

  Fly     8 VVGVLTLVAWWVL------------QNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTY 60
            ::..|||..|.:|            :.:..:|::|||...|             :|..|.:...|
  Rat     3 LLSALTLETWVLLAVVLVLLYGFGTRTHGLFKKQGIPGPKP-------------LPFFGTVLNYY 54

  Fly    61 L---KFRKQTD---GPFAGFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDRGVYHNEKD-DP--- 114
            :   ||..:..   |...|.:...|....|||.:.:|.||::: |      .|:.|.:| .|
  Rat    55 MGLWKFDVECHKKYGKIWGLFDGQMPLFAITDTEMIKNVLVKECF------SVFTNRRDFGPVGI 113

  Fly   115 LTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVS 179
            :...::..:.::||..|..|:.||||.::|.||..:...||.:::.:.::   ..:.:.|.::..
  Rat   114 MGKAISVSKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQE---KGKPVPVKEVFG 175

  Fly   180 RFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPS 244
            .::.|||...:||:..:||.:||..||:.....||       :|  .|....|:|.| |.||.|.
  Rat   176 AYSMDVITSTSFGVNVDSLNNPKDPFVEKAKKLLR-------ID--FFDPLFLSVVL-FPFLTPV 230

  Fly   245 VQ------------KFYMKIVQDTIDYRMKR------KVTRNDFMDTLIDMKQQYDKGDKENGLA 291
            .:            :|:.|.|     ||||.      :..|.||:..:  |....|..|||:..|
  Rat   231 YEMLNICMFPKDSIEFFKKFV-----YRMKETRLDSVQKHRVDFLQLM--MNAHNDSKDKESHTA 288

  Fly   292 FN--EVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDL 354
            .:  |:.||:.:|..||:|..|:|:.|.|:.||.:.|.|.||:.|||..|.. .....||::.::
  Rat   289 LSDMEITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPN-KAPPTYDTVMEM 352

  Fly   355 FYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIP 419
            .|::.|:||:||.:|:...|.|:..|..:.:.  .|:..|:.|::.:..:|.||:.:||||:|.|
  Rat   353 EYLDMVLNETLRLYPIGNRLERVCKKDVEING--VFMPKGSVVMIPSYALHRDPQHWPEPEEFRP 415

  Fly   420 ERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINN 484
            |||.:|.........:||||.|||||||:||..|.:.:.|..::.||.|:...:|.:|:|.:...
  Rat   416 ERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQG 480

  Fly   485 LL 486
            ||
  Rat   481 LL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	145/486 (30%)
Cyp3a23-3a1	NP_037237.2	p450	39..492	CDD:278495	145/486 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870