Protein Alignment Cyp6a19 and cyp-13A6

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_496113.1
• Gene: cyp-13A6 / 188357
• WormBaseID: WBGene00011673
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 144/545 - (26%)
• Similarity: 255/545 - (46%)
• Gaps: 93/545 - (17%)

  Fly     3 ILLGLVVGVLTLVAW-WVLQNYTYWKRRGI--PHDPPNIPLGNTGELWRTMPLAGILKRT----- 59
            :|..:::||.|...| |     :|:.|:||  |...|.|               |:|.:|
 Worm     5 LLSAVLLGVFTYSVWIW-----SYFIRKGIKGPRGFPGI---------------GMLIQTIDHEN 49

  Fly    60 --YLKFRKQTD--GPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRG----VYHNEKDDPLT 116
              :||:|..|.  ||..||.....:.::|::.:.|..:..:.||.|:.|.    :...|||..:
 Worm    50 PPFLKYRDWTKQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNFYGRKLRPIIGDPEKDKRV- 113

  Fly   117 NNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRF 181
             |:.:.:|::||.||...:.:|::..::.:.::|...|.|::..:::|: ..::.:::..:...:
 Worm   114 -NIFSTQGKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKV-RKNEDIDMLIVYQEY 176

  Fly   182 TSDVIGICAFG-LKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLA------VKLGFQ 239
            |..||...|.| .:.|..::|....||..::.      .|.|.|:....|.||      .|:...
 Worm   177 TLGVISRIALGQSESNMFKNPLLPKVQAIFNG------SWHVFLITGIFPPLAGVFRKMSKMLPA 235

  Fly   240 FLLPSVQKFYM--KIVQDTIDYRMKRKV------TRNDFMDTLID-----------------MKQ 279
            ..:|:.:.|.:  ..||..||.|.|.::      ...||:|..:|                 .|.
 Worm   236 SFIPAFKIFDLIEVAVQARIDQRAKDEIKGVEPGEPQDFIDLFLDARVPDVKILSGEANEDFAKS 300

  Fly   280 QYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNG 344
            ...|.:||  |.|:|:.||.|||..|||:..:.::.:..|.||.:.::|.||:.|:|.  |..:.
 Worm   301 SVVKINKE--LTFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEVDR--ECPDP 361

  Fly   345 KLEYDSMQDLFYMEKVINESLRKHPV--VAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHD 407
            ::.:|.:..|.|:|.|:.|:||.:|:  .|:..:...:  ...|...|.| |..:.|.|..:||:
 Worm   362 EIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRE--TTINGVNFDE-GMNIQVDTWTLHHN 423

  Fly   408 PEFYPEP-EKFIPERFDE---EQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRF 468
            |..:.|. |.|.|||::.   |.::...  :::|||:|||.|||:|..:|:..|.||.::..:.|
 Worm   424 PRIWGEDVEDFKPERWENGACEHLEHNG--SYIPFGSGPRQCIGMRLAQMEQKILLAQILKEYSF 486

  Fly   469 ELHPKTPVPMKYTINNLLLGSEGGI 493
            .....|.:|:| .:..|.|..|..|
 Worm   487 RTTKNTQIPVK-LVGKLTLSPESVI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	125/471 (27%)
cyp-13A6	NP_496113.1	CYP3A-like	61..511	CDD:410678	124/469 (26%)