Protein Alignment Cyp6a19 and cyp-13A4

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 141/556 - (25%)
• Similarity: 246/556 - (44%)
• Gaps: 123/556 - (22%)

  Fly     1 MAILL--GLVVGVLTLVAW-WVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTY-- 60
            :::|:  .|.:|.||...| |     ::|.|:|:...             |..|..|::.:.:
 Worm     3 LSLLIAGALFIGFLTYYIWIW-----SFWIRKGVKGP-------------RGFPFFGVILKFHDY 49

  Fly    61 -----LKFRKQTD--GPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTN- 117
                 ||..:.|.  |...|......|.:|:::.:||..|.::.||.|:.|.. :..:.||..|
 Worm    50 ENPGLLKLGEWTKKYGSIYGITEGVEKTLVVSNPEFVHEVFVKQFDNFYGRKT-NPIQGDPNKNK 113

  Fly   118 --NLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSR 180
              :|...:|.:||.||...:.||::..::.:.|||.....|::|.:|| .|:..:.:::.|....
 Worm   114 RAHLVLAQGHRWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLDE-ASAKGKAVDLLDYYQE 177

  Fly   181 FTSDVIGICAFGLKCNSL--RDP-------------KAEFVQMGYSALRERRHGWLVDLLIFGMP 230
            ||.|:||..|.| :..||  |:|             |..|:..|...:.    |.|:..|....|
 Worm   178 FTLDIIGRIAMG-QTESLMFRNPMLPKVKEIFKKGGKMPFLIAGVFPIA----GTLMRQLFMKFP 237

  Fly   231 KLAVKLGFQFLLPSVQKFYMKIVQDTIDYRMKRKVT-----------RNDFMDTLIDMKQQYD-- 282
            |.:...|.           |..::..::.|::::..           ..||:|..:|.:...|
 Worm   238 KFSPAFGI-----------MNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFI 291

  Fly   283 --------------KGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRA 333
                          |.||.  |.|:|:..|.|||.|||::..:.::.::.|.||.:.::|.||:.
 Worm   292 EEESTLGFAKSEVLKVDKH--LTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQE 354

  Fly   334 EIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYF-------- 390
            |:|.  |..:.::.:|.:..|.|||.|:.|:||.:|:.:.:          .|.|..
 Worm   355 EVDR--ECPDPEVTFDQISKLKYMECVVKEALRMYPLASLV----------HNRKCMKKTNVLGV 407

  Fly   391 -IEAGTGVLVSTLGIHHDPEFY-PEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRM 453
             |:.||.|.|.|..:|:||:.: .:..:|.|||::...........:||||.|||.|||:|...|
 Worm   408 EIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWETGDELFYAKGGYLPFGMGPRICIGMRLAMM 472

  Fly   454 QVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGS 489
            :..:.|..::..:.|:...:|.:|:|      |:||
 Worm   473 EEKLLLTHILKKYTFDTSTETEIPLK------LVGS 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	131/522 (25%)
cyp-13A4	NP_496111.1	p450	33..514	CDD:278495	131/521 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I2666
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780