Protein Alignment Cyp6a19 and cyp-13B2

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_510369.2
• Gene: cyp-13B2 / 187068
• WormBaseID: WBGene00010606
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 134/518 - (25%)
• Similarity: 225/518 - (43%)
• Gaps: 76/518 - (14%)

  Fly     1 MAILLGLV--VGVLTLVAWWVLQNYTYWKRRGIPHDPPNIP-LGNTGELW-RTMPLAGILKRTYL 61
            |.:::.||  :||:.....|:   ::||||||| ..|..:| :|:..:|. |..|...|:.:...
 Worm     1 MGVIVCLVAIIGVVAGYFKWI---HSYWKRRGI-EGPVGLPFIGSFYDLADREKPRGFIINKWTK 61

  Fly    62 KFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDR-------GVYHNEKDDPLTNNL 119
            .|     |...|:|...:..:|::|:|.::.:.|:.||.|:.|       |.....:::|.. ||
 Worm    62 MF-----GKVFGYYEGVIPVLVVSDLDMLQEMFIKKFDCFYARKTTNLIHGNLECSQEEPRV-NL 120

  Fly   120 ATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISS-SSQTLEVTDIVSRFTS 183
            ....|.:||.||...:..|:...:|.:..|   :.|.:..:||..... :.:...:.:....||.
 Worm   121 FAARGARWKRLRALASPAFSVKALKQIHET---MEDSVFSMVDHMSKQVNGEAFNIHEYYQEFTY 182

  Fly   184 DVIGICAFGLKCNSLRDPKAEFVQMGYSALRE------RRHGWLVDLLIFGMPKL---------A 233
            |||...|.|      :....:|...|...:::      |.:.|.:.::..|....         |
 Worm   183 DVISRLAMG------QTYSEQFNNEGVDIVKKIFLRKNRVYPWYLAVMFPGFENTIKNTFFNHEA 241

  Fly   234 VKLGFQFLLPSVQKFYMKIVQDTIDYRMKRKV---------TRNDFMDTLIDMKQQYDKGDK--- 286
            |:.|      .|.|. :|..:..:..|:|.:.         ..|||:|..:|.....:..|.
 Worm   242 VRGG------DVGKL-LKFCETAVHDRLKERADNVEQGIENPHNDFIDMFLDYYTDTNIEDNAFG 299

  Fly   287 ---ENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEY 348
               |..:...:|....|||.||||:..:.|:.:..|.||.:.....|::.|||.:..  :..:.|
 Worm   300 IKVEKKVTSEDVIGACFVFLLAGFDTTANTLAYASYLLAKHPQEMRKVQDEIDRICT--SEHISY 362

  Fly   349 DSMQDLFYMEKVINESLRKHPVV-AHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFY- 411
            |.:..|.||:.||.|:||.:||. ...:|...:.....|  |:||.|..:......:|:..|.:
 Worm   363 DDIGKLRYMDAVIREALRMYPVAWFACSRECVQATTLGN--YYIEKGVRIEADVRALHYSEEIWG 425

  Fly   412 PEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKT 474
            ....:|:|||:.|.  ..|...:::|||||||.|:|:|.|..:....||.|:..|.....|||
 Worm   426 KNANEFVPERWLES--SPRHNMSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRFSILAGPKT 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	113/448 (25%)
cyp-13B2	NP_510369.2	CYP3A-like	62..505	CDD:410678	114/453 (25%)