Protein Alignment Cyp6a19 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 156/550 - (28%)
• Similarity: 262/550 - (47%)
• Gaps: 89/550 - (16%)

  Fly     1 MAI----LLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYL 61
            |||    :|..::|||:...|    .::|||||||. .|...|:     |...:.:.......||
 Worm     1 MAIIFLAILTSIIGVLSFYLW----TWSYWKRRGIA-GPSGYPI-----LGSALEMLSSENPPYL 55

  Fly    62 KFRKQTD--GPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTN---NLAT 121
            :.::.|.  |...|......:.:||:|.|.|:.|.::.:|.|..|.: :..:.||..:   ||.:
 Worm    56 QLKEWTKQYGKVYGITEGLSRTLVISDPDLVQEVFVKQYDNFFGRKL-NPIQGDPNKDKRVNLFS 119

  Fly   122 IEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVI 186
            .:|.:||.||...:.||::..::.:.:||.....|::|.: |:.:...|.:::.|....||.|||
 Worm   120 SQGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHI-EQHTDGGQPIDLLDFYQEFTLDVI 183

  Fly   187 GICAFGLKCNSL-RDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLG-----FQFLLPSV 245
            |..|.|...:.: ::|...:|:   :...|.|.|      :|....||..:|     ..|.||::
 Worm   184 GRIAMGQTDSQMFKNPLLPYVR---AVFGEPRKG------LFLSGSLAPWIGPILRMVMFSLPNI 239

  Fly   246 QK----FYMKIVQDTIDYRMKRKVT----------RNDFMDTLIDMKQQYDKGDKENG------- 289
            .|    ..::...:.::.|:|.::.          ..||:|..:|.|.  |..:.||.
 Worm   240 VKNPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKS--DDVELENNEDFTKAG 302

  Fly   290 ------LAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEY 348
                  |...|:..|.|||.:|||:..:.::.::.:.||.:..||.||:.|||.  |..:.::.:
 Worm   303 VKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDR--ECADPEVTF 365

  Fly   349 DSMQDLFYMEKVINESLRKHPVVAHLA--RIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFY 411
            |.:..|.|||.||.|:||.:|:.| ||  |...:..:..|  |.|:.||.:|..|..:|.|...:
 Worm   366 DQLSKLKYMECVIKETLRMYPLGA-LANSRCCMRATKIGN--YEIDEGTNILCDTWTLHSDKSIW 427

  Fly   412 PE-PEKFIPERF---DEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHP 472
            .| .|:|.|||:   ||...:|.   .::|||.|||.|||:|...|:..:.|:.::..:..|:..
 Worm   428 GEDAEEFKPERWESGDEHFYQKG---GYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEVCN 489

  Fly   473 KTPVPMKYTINNLLLGSE----GGIHLNIT 498
            ||.:|:|      |:||.    ..:.||:|
 Worm   490 KTQIPLK------LIGSRTTQPESVWLNLT 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	133/474 (28%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	132/470 (28%)