Protein Alignment Cyp6a19 and cyp-13A11

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_499704.1
• Gene: cyp-13A11 / 184472
• WormBaseID: WBGene00008809
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 155/564 - (27%)
• Similarity: 260/564 - (46%)
• Gaps: 118/564 - (20%)

  Fly     1 MAILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYLKFRK 65
            |.|||.:|..|:.:|::: ...:|||:|.||| .|...|.     |...:.:.......:|:.:|
 Worm     1 MIILLFVVSSVVGIVSYY-FWTWTYWRRCGIP-GPQGYPF-----LGSALDMMDHENPPFLQLKK 58

  Fly    66 QTD--GPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATI---EGQ 125
            .|.  |...|.....::.:||:|.:.:..|.::.:|.|:.|.: :..:.||......|:   :|.
 Worm    59 WTSQYGKVYGITEGLLRTLVISDTNLIHEVFVKQYDNFYGRNL-NPIQGDPNREKRVTLFSAQGH 122

  Fly   126 KWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICA 190
            :||.||.....||:|..::.:..||.:...|::|.: |:.::..:.::|.:....||.||||..|
 Worm   123 RWKRLRTIANPTFSSNNLRKIQVTVEDSALELLRHI-EQHTAGGKAIDVLEYFQEFTMDVIGRIA 186

  Fly   191 FG-----------LKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLG---FQFL 241
            .|           |.|  .||                         :||.|:.|:.|.   |.::
 Worm   187 MGQPDSLMFKNPLLPC--ARD-------------------------VFGKPRTALFLSGILFPWI 224

  Fly   242 LPSVQK--FYM---------KIVQDT---IDYRMKRKVTR----------NDFMDTLIDMKQQYD 282
            .|.::|  ||.         :|:..|   ::.|:|:::..          .||:|..:|.|.  |
 Worm   225 GPMIRKVVFYFTNVFNNPAAQIMYQTANAVEQRIKQRMAEEKAGIDPGEPQDFIDLFLDAKS--D 287

  Fly   283 KGDKENG-------------LAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAE 334
            ..:.||.             |..:||..|.|||.:|||:..:.::.::.:.||.:...|.||:.|
 Worm   288 DMELENNEDFTKAGVKVTRQLTKDEVVGQCFVFLIAGFDTTALSLSYSSFLLATHPKAQKKLQEE 352

  Fly   335 IDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLA--RIATKPYQHSNPKYFIEAGTGV 397
            ||.  |..:.::.:|.:..|.|||.||.|:||.:|:.| ||  |...:..:..|  |.||.|..:
 Worm   353 IDR--ECADPEVTFDQLSKLKYMECVIKETLRMYPLGA-LANSRRCMRSTKIGN--YEIEKGVDI 412

  Fly   398 LVSTLGIHHDPEFYPE-PEKFIPERF---DEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIG 458
            |..|..:|:|...:.| .|:|.|||:   ||...:|.   .::|||.|||.|||:|...|:..:.
 Worm   413 LCDTWTLHYDKSIWGEDAEEFKPERWESGDEHFYQKG---GYIPFGLGPRQCIGMRLAYMEEKLL 474

  Fly   459 LALLIHNFRFELHPKTPVPMKYTINNLLLGSE----GGIHLNIT 498
            |:.::..:..|:..||.:|:|      |:||.    ..:.||:|
 Worm   475 LSHILRKYTLEVCNKTQIPLK------LIGSRTTQPESVWLNLT 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	133/492 (27%)
cyp-13A11	NP_499704.1	CYP3A-like	62..506	CDD:410678	132/488 (27%)