Protein Alignment Cyp6a19 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 149/524 - (28%)
• Similarity: 229/524 - (43%)
• Gaps: 80/524 - (15%)

  Fly     1 MAILLGLVVGVLTLVAWWVLQNYTYWKRR---GIPHDPPNIPLGNTGELWRTMPLAGI--LKRTY 60
            :.||..||:.:.|...:.:|.....:|.|   |:....|:..|||..:........|.  ..|.:
 Worm     3 LLILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDANRWF 67

  Fly    61 LKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNN-LATIEG 124
            .:..:|....| |.|..:...|||::...:|.|.|::|..|.||.|....:.:.||.: |.....
 Worm    68 NELHEQYGETF-GIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNSYS 131

  Fly   125 QKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGIC 189
            ..||:.|..:...|::.|||:|..|:.:..|..:.::.|| :||.|..::.|.....|.||||.|
 Worm   132 SGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREK-ASSGQKWDIYDDFQGLTLDVIGKC 195

  Fly   190 AFGLKCNSLRDPKAEFV--QMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKI 252
            ||.:..|..||....|.  ...|.:..:.||..::...:              |||.:..|:..:
 Worm   196 AFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASV--------------LLPELSTFWKAL 246

  Fly   253 VQDT---------ID-----YRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFF 303
            .:.|         ::     |..:|....:|.:|.|..:..:.|  ||...:...||....|.|.
 Worm   247 YKYTPLADAEIPLVEGLSNVYERRRGGEGSDSVDLLKLLLNRED--DKSKPMTKQEVIENCFAFL 309

  Fly   304 LAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKH 368
            |||:|..||.|.:..|.|:...:||.||..||....|  ||.|.|||:.::.|::.|..|:||.:
 Worm   310 LAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKE--NGGLTYDSIHNMKYLDCVYKETLRFY 372

  Fly   369 PVVAHLAR--------IATKPYQHSNPKYFIEAGTGVLVSTL--GIHHDPEFYPEPEKFIPERFD 423
            |.|.|..|        |..:.|    ||       |.:|..|  .:|.:||.:..||:|.||||
 Worm   373 PPVIHFIRRLCREDITIRGQFY----PK-------GAIVVCLPHTVHRNPENWDSPEEFHPERF- 425

  Fly   424 EEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNF---RFE-------------LHP 472
            |...:|..:..::|||.|||.|:|:||..|:....:..|:..|   :||             :.|
 Worm   426 ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFEGEADLIPDCNGVIMRP 490

  Fly   473 KTPV 476
            ..||
 Worm   491 NDPV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	133/453 (29%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	134/454 (30%)