Protein Alignment Cyp6a19 and cyp-25A2

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 144/530 - (27%)
• Similarity: 229/530 - (43%)
• Gaps: 90/530 - (16%)

  Fly     1 MAILLGLVVGVLTLVAWWVLQNYTYWKRR---------GIPHDPPNIPLGNTGELWRTMPLAGI- 55
            ||:|  ::..:|.|:..:::  |..:.||         |:....|:..:||..::.......|.
 Worm     1 MALL--ILTSILILLVSFII--YILFARREQFKLREKIGLTGPEPHWFMGNLKQIVDRKEKLGYD 61

  Fly    56 -LKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGV-----YHNEKDDP 114
             ..:.:.:..||....| |.|..|...||:::.:.:|.|.|::|..|.||.|     .:......
 Worm    62 DSNKWFNELHKQYGETF-GIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQLNQSL 125

  Fly   115 LTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVS 179
            |.|..||    .||:.|..:...|::.|||:|..|:.:..|..:.::.|| :||.|..::.:...
 Worm   126 LQNTYAT----GWKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREK-ASSGQKWDIYEDFQ 185

  Fly   180 RFTSDVIGICAFGLKCNSLRDPKAEFV--QMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLL 242
            ..|.||||.|||.:..|..||....|.  ...:.|..:.||..::              ...|:|
 Worm   186 GLTLDVIGKCAFAIDSNCQRDRNDVFYVNARKFIANIDIRHSKVI--------------AASFIL 236

  Fly   243 PSVQKFYMKIVQDT---------ID-----YRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFN 293
            |.:...:..:.:.|         ::     |..:|....:|.:|.|..:..:.|  ||...:...
 Worm   237 PELAPLWRALYKYTPLADAEIPLVEGLSNVYERRRGGEGSDSVDLLKLLLNRED--DKSKPMTKQ 299

  Fly   294 EVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYME 358
            ||....|.|.|||:|..||.|.:..|.|:...:||.||..||....|  ||.|.|||:.::.|::
 Worm   300 EVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKE--NGGLTYDSIHNMKYLD 362

  Fly   359 KVINESLRKHPVVAH------LARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKF 417
            .|..|:||.:|.|.|      ||.|..:       ..|...|:.|......:|.:||.:..||:|
 Worm   363 YVYKETLRCYPPVIHFINRRCLADITIR-------GQFYPKGSVVTCLPHTVHLNPENWDSPEEF 420

  Fly   418 IPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFE------------- 469
            .|||| |...:|..:..::|||.|||.|:|:||..|:....:..|:..|..:
 Worm   421 HPERF-ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFKGEADLIPDCN 484

  Fly   470 ---LHPKTPV 476
               :.||.||
 Worm   485 GVIMRPKDPV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	129/453 (28%)
cyp-25A2	NP_497776.2	CYP3A-like	73..495	CDD:410678	130/454 (29%)