Protein Alignment Cyp6a19 and cyp-13A10

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_496085.3
• Gene: cyp-13A10 / 174522
• WormBaseID: WBGene00014254
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 152/541 - (28%)
• Similarity: 256/541 - (47%)
• Gaps: 104/541 - (19%)

  Fly     1 MAILL----GLVVGVLTLVAW-WVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRT- 59
            |:::|    .|.:|.::...| |     |||:|||||.     |||        .||.|...:|
 Worm     1 MSVILLAIPTLFIGFISYYLWIW-----TYWRRRGIPG-----PLG--------YPLVGSFPKTL 47

  Fly    60 ------YLKFRKQTD--GPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVY----HNEKD 112
                  ||:.|..|.  ||..|:....:|.::::|:|.|:.:.:..:|.|:.|.:.    ..|||
 Worm    48 KSEYPQYLQIRDWTKLYGPIYGYTEGTIKTLIVSDIDIVRQIFVEQYDNFYGRKLNPIQGDPEKD 112

  Fly   113 DPLTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDI 177
            :  ..||.:.:|.:||.||...:.||::..::.:..||.:...|::|.::|: :|..|.:::...
 Worm   113 E--RTNLFSAQGFRWKRLRAISSPTFSNNSLRKINVTVEDSAMELLRHIEEQ-TSEGQQIDMLQF 174

  Fly   178 VSRFTSDVIGICAFGLKCNSL-RDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFL 241
            ...||.|.||..|.|...:.: ::|..:||:..:.  ..|:|   :.|:....|.||....| |:
 Worm   175 YQEFTMDTIGRIAMGQTDSQMFKNPLLKFVRAIFG--DNRKH---IPLIGGVFPTLAQVFRF-FM 233

  Fly   242 LP----------SVQKFYMKIVQDTIDYRMKRKVTRN--------DFMDTLIDMKQ------QYD 282
            |.          .|.|..:..||:.||.|...:  :|        ||:|..::.:.      |.:
 Worm   234 LKFPLLGAANFIHVNKTVVTAVQNRIDQRENDR--KNGIEIGEPQDFIDLFLEARADDVEHFQEN 296

  Fly   283 KGD-------KENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLE 340
            .||       ....|...|:..|..||.:|||:..:.::.:|.:.||.:.:||.||:.||:.  |
 Worm   297 NGDFSKTSSYGNRQLTTQEIVGQCLVFLIAGFDTTALSLSYTTFLLATHPEVQKKLQEEIER--E 359

  Fly   341 RYNGKLEYDSMQDLFYMEKVINESLRKHPV--VAHLARI--ATKPYQHSNPKYFIEAGTGVLVST 401
            .....:.:|.:..|.||:.:|.|:||.:|:  :|:..|.  |||   ..|.:  :|.||.|.|.|
 Worm   360 CIEPSISFDHLSKLKYMDCIIKETLRLYPLGTMANSRRCMRATK---LGNVE--VEVGTMVQVDT 419

  Fly   402 LGIHHDPEFYPEPEK-FIPERFDEEQVKKRPTC-------AFLPFGAGPRNCIGLRFGRMQVIIG 458
            ..:|.|.:.:.:..| |.|||:.:      |.|       .::.||.|||.|:|:|...|:..:.
 Worm   420 WSLHTDTKIWGDDAKEFKPERWLD------PNCDQVFQKGGYISFGLGPRQCVGMRLAYMEEKML 478

  Fly   459 LALLIHNFRFELHPKTPVPMK 479
            ||.::..:.||:..||.:|:|
 Worm   479 LAHILRKYTFEVGTKTEIPLK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	139/505 (28%)
cyp-13A10	NP_496085.3	p450	32..500	CDD:278495	139/505 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16885
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760